Key features and details
- Highly potent, selective CRTH2/DP2 antagonist
- CAS Number: 627865-18-3
- Purity: > 98%
- Soluble in ethanol to 25 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Product nameCAY10471, CRTH2/DP2 antagonist
DescriptionHighly potent, selective CRTH2/DP2 antagonist
Highly potent, selective CRTH2/DP2 antagonist (Ki values are 0.6, 1200 and 10,000 nM for DP2, DP1 and TP respectively). BAY-u3405 (ab142763) analog. Shows renoprotective effects in vivo. Orally active.
Chemical name2-[3-[(4-Fluorophenyl)sulfonyl-methylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]acetic acid
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol to 25 mM and in DMSO to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipoprotein metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144459 has not yet been referenced specifically in any publications.