Overview

  • Product name

    CAY10498, A3 adenosine receptor antagonist
  • Description

    Potent, selective A3 adenosine receptor antagonist
  • Biological description

    Potent, selective A3 adenosine receptor antagonist (Ki = 37 nM). Reversine (ab120921) analog.
  • Purity

    > 98%
  • CAS Number

    863202-33-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    6-N-(3-Bicyclo[2.2.1]heptanyl)-2-N-phenyl-7H-purine-2,6-diamine
  • Molecular weight

    320.40
  • Molecular formula

    C18H20N6
  • PubChem identifier

    53394567
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1CC2CC1CC2NC3=NC(=NC4=C3NC=N4)NC5=CC=CC=C5
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Perreira M  et al. "Reversine" and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists. J Med Chem 48:4910-8 (2005). Read more (PubMed: 16033270) »

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