Key features and details
- Sheep polyclonal to CCBL1
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Product nameAnti-CCBL1 antibody
See all CCBL1 primary antibodies
DescriptionSheep polyclonal to CCBL1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse
Predicted to work with: Rat, Human
Recombinant fragment corresponding to Human CCBL1 aa 182-422. (Derived from S.frugiperda insect ovarian cell line Sf 21).
TPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIAS LPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCP TQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKP IIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPV SIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVEL
Database link: Q16773
- Mouse kidney lysate.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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FormLyophilized:Reconstitute the antibody with 100 uL sterile PBS and the final concentration is 500 ug/mL. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferConstituent: 100% PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesThe IgG fraction of immunized serum was purified by antigen affinity chromatography and lyophilized from a 0.2 µm filtered solution in phosphate-buffered saline (PBS).
Our Abpromise guarantee covers the use of ab215056 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/2000. Detects a band of approximately 45 kDa (predicted molecular weight: 48 kDa).|
RelevanceCCBL1 is a cytosolic enzyme which is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism leads to the formation of reactive metabolites which can lead to nephrotoxicity and neurotoxicity. CCBL1 catalyzes the irreversible transamination of the L-tryptophan metabolite L-kinurenine to form kynurenic acid (KA). It catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. This enzyme has a central role in the bioactivation of nephrotoxic halogenated hydrocarbons - the possibility of human exposure to these chemicals has focused interest on the CCBL1 from human kidney.
- Beta lyase antibody
- Beta lysase, kidney antibody
- CCBL 1 antibody
Anti-CCBL1 antibody (ab215056) at 1/1000 dilution + mouse kidney lysate
Predicted band size: 48 kDa
Observed band size: 45 kDa why is the actual band size different from the predicted?
ab215056 has not yet been referenced specifically in any publications.