Key features and details
- Rabbit polyclonal to CCDC50
- Suitable for: WB
- Reacts with: Human, Chimpanzee, Monkey
- Isotype: IgG
Product nameAnti-CCDC50 antibody
See all CCDC50 primary antibodies
DescriptionRabbit polyclonal to CCDC50
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human, Chimpanzee, Monkey
Predicted to work with: Rat, Cow, Dog
A portion of amino acids 450-500 of human CCDC50 (NP_777568).
- Human, mouse and rat skeletal muscle lysate.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: 0.05% BSA, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab72082 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.05 - 0.5 µg/ml. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).|
FunctionInvolved in EGFR signaling.
Tissue specificityIsoform 1 and isoform 2 are co-expressed in placenta, liver, lung, kidney and pancreas. Only isoform 1 is detected in skeletal muscle, brain and heart.
Involvement in diseaseDefects in CCDC50 are the cause of deafness autosomal dominant type 44 (DFNA44) [MIM:607453]. A form of non-syndromic hearing loss. It is initially moderate and affects mainly low to mid frequencies. Later, it progresses to involve all the frequencies and leads to a profound hearing loss by the 6th decade. The onset of the hearing loss occurs in the first decade of life.
modificationsPhosphorylated on tyrosine residues.
Cellular localizationCytoplasm. Associated with microtubules of the cytoskeleton and mitotic apparatus.
- Information by UniProt
- C3orf6 antibody
- C3orf6 YMER antibody
- CCD50_HUMAN antibody
Lanes 1-2 : Anti-CCDC50 antibody (ab72082) at 0.05 µg/ml
Lanes 3-4 : Anti-CCDC50 antibody (ab72082) at 0.25 µg/ml
Lane 1 : Human skeletal muscle lysate
Lane 2 : Human skeletal muscle lysate plus immunizing peptide
Lane 3 : Mouse skeletal muscle lysate
Lane 4 : Rat skeletal muscle lysate
Predicted band size: 36 kDa
Observed band size: 36 kDa
ab72082 has not yet been referenced specifically in any publications.