Key features and details
- Rabbit polyclonal to CCDC6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-CCDC6 antibody
See all CCDC6 primary antibodies
DescriptionRabbit polyclonal to CCDC6
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Zebrafish
Recombinant fragment corresponding to a region within amino acids 1-222 of Human CCDC6. (Uniprot:Q16204)
- HepG2 whole cell lysate (ab7900)
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab155212 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 53 kDa.|
Tissue specificityUbiquitously expressed.
Involvement in diseaseDefects in CCDC6 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving CCDC6 is found in thyroid papillary carcinomas. Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene.
DomainThe protein has mostly an alpha helical conformation similar to myosin heavy-chain tail that might adopt a coiled-coil conformation.
Cellular localizationCytoplasm. Cytoplasm > cytoskeleton. May be a cytoskeletal protein.
- Information by UniProt
- CCDC 6 antibody
- CCDC6 antibody
- CCDC6_HUMAN antibody
ab155212 has not yet been referenced specifically in any publications.