Overview

  • Product name
  • Description
    Rabbit polyclonal to CCDC8
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human CCDC8 aa 397-426 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q9H0W5

  • Positive control
    • Jurkat cell line lysate, Human tonsil tissue

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab170233 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 59 kDa.

Target

  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Information by UniProt
  • Database links
  • Alternative names
    • CCDC8 antibody
    • CCDC8_HUMAN antibody
    • Coiled coil domain containing 8 antibody
    • Coiled-coil domain-containing protein 8 antibody
    • DKFZp564K0322 antibody
    • ENSMUSG00000041117 antibody
    • MGC72567 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded Human tonsil tissue labeling CCDC8 with ab170233 at 1/50.

  • Anti-CCDC8 antibody (ab170233) at 1/100 dilution + Jurkat cell line lysate at 35 µg

    Predicted band size: 59 kDa

References

This product has been referenced in:
  • Pangeni RP  et al. The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain. Clin Epigenetics 7:57 (2015). WB . Read more (PubMed: 26052355) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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