Overview

  • Product name
  • Description
    Rabbit polyclonal to CCK1-R
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Guinea pig
  • Immunogen

    Synthetic peptide corresponding to Human CCK1-R aa 197-210. Poly Lysin conjugated synthetic peptide.
    Sequence:

    RFLLPPNDVMQQSWH

  • General notes

    Protein previously labeled as CCKAR.

Properties

Applications

Our Abpromise guarantee covers the use of ab14441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Detects a band of approximately 48 kDa.

Target

  • Function
    Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CCK A antibody
    • CCK A receptor antibody
    • CCK AR antibody
    • CCK-A receptor antibody
    • CCK-AR antibody
    • CCK1 R antibody
    • CCK1-R antibody
    • CCK1R antibody
    • CCKA antibody
    • CCKA receptor antibody
    • CCKAR antibody
    • CCKAR_HUMAN antibody
    • CCKR Type A antibody
    • CCKRA antibody
    • Cholecystokinin 1 receptor antibody
    • Cholecystokinin A receptor antibody
    • Cholecystokinin receptor type A antibody
    • Cholecystokinin type A receptor antibody
    • Cholecystokinin-1 receptor antibody
    see all

References

ab14441 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunocytochemistry
Sample
Human Cultured Cells (transfected HEK293)
Permeabilization
Yes - 0.3%TritonX-100
Specification
transfected HEK293
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 25°C
Fixative
Methanol

Abcam user community

Verified customer

Submitted Sep 14 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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