Key features and details
- Rabbit polyclonal to CCK1-R
- Suitable for: WB, ELISA
- Reacts with: Human
- Isotype: IgG
Product nameAnti-CCK1-R antibody
See all CCK1-R primary antibodies
DescriptionRabbit polyclonal to CCK1-R
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to Human CCK1-R (internal sequence).
- Extracts from HUVEC cells.
Protein previously labeled as CCKAR.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab75153 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 48 kDa.|
FunctionReceptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- CCK A antibody
- CCK A receptor antibody
- CCK AR antibody
All lanes : Anti-CCK1-R antibody (ab75153) at 1/500 dilution
Lane 1 : Extracts from HUVEC cells
Lane 2 : Extracts from HUVEC cells with immunising peptide at 5 µg
Lysates/proteins at 5 µg per lane.
Predicted band size: 48 kDa
Observed band size: 45 kDa why is the actual band size different from the predicted?
ab75153 has been referenced in 2 publications.
- Guo L et al. Inhibitory effect of high leucine concentration on a-amylase secretion by pancreatic acinar cells: possible key factor of proteasome. Biosci Rep 38:N/A (2018). PubMed: 30361293
- Duraisamy AJ et al. Changes in ghrelin, CCK, GLP-1, and peroxisome proliferator-activated receptors in a hypoxia-induced anorexia rat model. Endokrynol Pol 66:334-41 (2015). PubMed: 26323471