Overview

  • Product name

  • Description

    Rabbit polyclonal to CCK1-R
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human CCK1-R (internal sequence).

  • Positive control

    • Extracts from HUVEC cells.
  • General notes

    Protein previously labeled as CCKAR.

Properties

Applications

Our Abpromise guarantee covers the use of ab75153 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 48 kDa.
ELISA 1/10000.

Target

  • Function

    Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CCK A antibody
    • CCK A receptor antibody
    • CCK AR antibody
    • CCK-A receptor antibody
    • CCK-AR antibody
    • CCK1 R antibody
    • CCK1-R antibody
    • CCK1R antibody
    • CCKA antibody
    • CCKA receptor antibody
    • CCKAR antibody
    • CCKAR_HUMAN antibody
    • CCKR Type A antibody
    • CCKRA antibody
    • Cholecystokinin 1 receptor antibody
    • Cholecystokinin A receptor antibody
    • Cholecystokinin receptor type A antibody
    • Cholecystokinin type A receptor antibody
    • Cholecystokinin-1 receptor antibody
    see all

Images

  • All lanes : Anti-CCK1-R antibody (ab75153) at 1/500 dilution

    Lane 1 : Extracts from HUVEC cells
    Lane 2 : Extracts from HUVEC cells with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.

    Predicted band size: 48 kDa
    Observed band size: 45 kDa
    why is the actual band size different from the predicted?

References

This product has been referenced in:

  • Guo L  et al. Inhibitory effect of high leucine concentration on a-amylase secretion by pancreatic acinar cells: possible key factor of proteasome. Biosci Rep 38:N/A (2018). Read more (PubMed: 30361293) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab75153.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up