Overview

  • Product name

    Anti-CCL28/MEC antibody [EPR12933]
    See all CCL28/MEC primary antibodies
  • Description

    Rabbit monoclonal [EPR12933] to CCL28/MEC
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Recombinant fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment within Human CCL28/MEC aa 1 to the C-terminus. The exact sequence is proprietary.
    Database link: Q9NRJ3

  • Positive control

    • CCL28/MEC recombinant protein.
  • General notes

     

     

     This product was previously labelled as CCL28

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab192600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Detects a band of approximately 14 kDa (predicted molecular weight: 14 kDa).

Target

  • Function

    Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.
  • Tissue specificity

    Preferentially expressed by epithelial cells of diverse tissues including normal and pathological colon, salivary gland, mammary gland, trachea and rectum. Also found in prostate, spleen, thyroid, psoriasis skin and in lower levels in peripheral blood leukocytes, small intestine, Peyer patches, stomach and normal skin.
  • Sequence similarities

    Belongs to the intercrine beta (chemokine CC) family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • C C motif chemokine ligand 28 antibody
    • C-C motif chemokine 28 antibody
    • CC chemokine CCL28 antibody
    • CCK 1 antibody
    • CCK1 antibody
    • CCK1 protein antibody
    • CCL 28 antibody
    • CCL28 antibody
    • CCL28_HUMAN antibody
    • Chemokine (C-C motif) ligand 28 antibody
    • chemokine (C-C motif) ligand 28 splice variant chi antibody
    • MEC antibody
    • Mucosae associated epithelial chemokine antibody
    • Mucosae-associated epithelial chemokine antibody
    • Protein CCK1 antibody
    • SCYA28 antibody
    • Small inducible cytokine A28 [Precursor] antibody
    • small inducible cytokine subfamily A (Cys-Cys), member 28 antibody
    • Small-inducible cytokine A28 antibody
    see all

Images

  • Anti-CCL28/MEC antibody [EPR12933] (ab192600) at 1/50000 dilution + CCL28/MEC recombinant protein at 10 µg

    Secondary
    goat anti-rabbit IgG, (H+L), peroxidase conjugated at 1/1000 dilution

    Developed using the ECL technique.

    Predicted band size: 14 kDa
    Observed band size: 14 kDa

  • Anti-CCL28/MEC antibody [EPR12933] (ab192600) at 1/1000 dilution + Human milk at 10 µg

    Secondary
    VeriBlot for IP Detection Reagent (HRP) (ab131366) at 1/10000 dilution

    Predicted band size: 14 kDa
    Observed band size: 14 kDa


    Exposure time: 3 minutes


    Blocking/Diluting buffer 5% NFDM /TBST. 

    This target is mainly expressed in some exocrine glands such as mammary gland and salivary gland, and is secreted into milk or saliva.(PMID: 20688401; PMID: 12538707). 

References

ab192600 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab192600.
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