• Product name

    Anti-CCL4/MIP-1 beta antibody
    See all CCL4/MIP-1 beta primary antibodies
  • Description

    Goat polyclonal to CCL4/MIP-1 beta
  • Host species

  • Specificity

    Human MIP1 beta neutralizes the of bioactivity of recombinant, human MIP1 beta, but not that of recombinant, mouse MIP1 beta, recombinant, human MIP1 alpha or recombinant, mouse MIP1 beta. In indirect ELISA and immunoblotting, this antibody displays approximately 8% cross-reactivity with recombinant, mouse MIP1 alpha, recombinant, human MIP1 alpha and recombinant, mouse MIP1 beta. The product shows no cross-reactivity with other tested cytokines using indirect ELISA.
  • Tested applications

    Suitable for: ELISA, WB, Neutralisingmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant full length protein corresponding to Human CCL4/MIP-1 beta.

  • General notes

    Endotoxin: <10 ng/vial.

    This product was lyopholized in PBS with trehalose.


     This product was previously labelled as Macrophage Inflammatory Protein 1 beta, MIP1 beta




Our Abpromise guarantee covers the use of ab10384 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notes
    ELISA: Use at a concentration of 0.125 µg/ml to detect 1ng/well of recombinant human MIP1 beta.
    Neut: Use at a concentration of 30 µg/ml.
    WB: Use at a concentration of 1 µg/ml to detect 2ng/lane of recombinant human MIP1 beta under non-reducing conditions. Predicted molecular weight: 11 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.
    • Post-translational

      N-terminal processed form MIP-1-beta(3-69) is produced by proteolytic cleavage after secretion from peripheral blood lymphocytes.
    • Cellular localization

    • Information by UniProt
    • Database links

    • Alternative names

      • MIP 1 beta antibody
      • Secreted protein G 26 antibody
      • ACT 2 antibody
      • ACT-2 antibody
      • ACT2 antibody
      • AT744.1 antibody
      • AT744.2 antibody
      • C C motif chemokine 4 antibody
      • C C motif chemokine 4 like antibody
      • C C motif chemokine ligand 4 like 1 antibody
      • C C motif chemokine ligand 4 like 2 antibody
      • CC chemokine ligand 4 antibody
      • CC chemokine ligand 4L1 antibody
      • CC chemokine ligand 4L1d2 antibody
      • CC chemokine ligand 4L2 antibody
      • CCL4 antibody
      • CCL4_HUMAN antibody
      • ccl4l 1 antibody
      • CCL4L antibody
      • CCL4L1 antibody
      • Chemokine (C C motif) ligand 4 antibody
      • Chemokine (C C motif) ligand 4 like 1 antibody
      • Chemokine (C C motif) ligand 4 like 1, telomeric antibody
      • Chemokine (C C motif) ligand 4 like 2 antibody
      • Chemokine CC Motif Ligand 4 antibody
      • G 26 antibody
      • G 26 T lymphocyte secreted protein antibody
      • G-26 T-lymphocyte-secreted protein antibody
      • HC21 antibody
      • Immune activation 2 antibody
      • LAG 1 antibody
      • LAG-1 antibody
      • LAG1 antibody
      • Lymphocyte activation gene 1 antibody
      • Lymphocyte activation gene 1 protein antibody
      • Macrophage inflammatory protein 1 beta antibody
      • Macrophage inflammatory protein 1-beta antibody
      • Macrophage inflammatory protein 1b2 antibody
      • MGC104418 antibody
      • MGC126025 antibody
      • MGC126026 antibody
      • MIP-1-beta antibody
      • MIP-1-beta(1-69) antibody
      • MIP-1-beta(3-69) antibody
      • MIP1 beta antibody
      • MIP1B antibody
      • MIP1B1 antibody
      • Monocyte adherence induced protein 5 alpha antibody
      • PAT 744 antibody
      • Protein H400 antibody
      • SCYA2 antibody
      • SCYA4 antibody
      • SCYA4L antibody
      • SCYA4L1 antibody
      • SCYA4L2 antibody
      • SCYQ4L2 antibody
      • Secreted protein G 26 antibody
      • Secreted protein G26 antibody
      • SIS gamma antibody
      • SIS-gamma antibody
      • Small inducible cytokine A4 (homologous to mouse Mip 1b) antibody
      • Small inducible cytokine A4 antibody
      • small inducible cytokine A4-like antibody
      • Small-inducible cytokine A4 antibody
      • T cell activation protein 2 antibody
      • T-cell activation protein 2 antibody
      see all


    This product has been referenced in:

    • Schmidt J  et al. Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle. Brain 131:1228-40 (2008). IHC-P ; Human . Read more (PubMed: 18420712) »
    See 1 Publication for this product

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