Overview

  • Product name

  • Description

    Mouse polyclonal to CCNB1IP1
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    CCNB1IP1 (NP_878269.1) full length human protein

  • Positive control

    • CCNB1IP1 transfected lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab71977 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 32 kDa.

Target

  • Function

    E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.
  • Tissue specificity

    Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung.
  • Pathway

    Protein modification; protein ubiquitination.
  • Sequence similarities

    Contains 1 RING-type zinc finger.
  • Post-translational
    modifications

    Ubiquitinated; autoubiquitinated.
    Phosphorylated by CDK1 on serine or threonine residues (in vitro).
  • Cellular localization

    Nucleus. Chromosome. May associate with segregating chromosomes during metaphase and anaphase.
  • Information by UniProt
  • Database links

  • Alternative names

    • C14orf18 antibody
    • CCNB1IP1 antibody
    • Chromosome 14 open reading frame 18 antibody
    • CIP1_HUMAN antibody
    • Cyclin B1 interacting protein 1 antibody
    • cyclin B1 interacting protein 1, E3 ubiquitin protein ligase antibody
    • Cyclin-B1-interacting protein 1 antibody
    • E3 ubiquitin-protein ligase CCNB1IP1 antibody
    • Enhancer of invasion 10 antibody
    • Gm288 antibody
    • HEI10 antibody
    • Human enhancer of invasion 10 antibody
    • mei4 antibody
    see all

Images

  • All lanes : Anti-CCNB1IP1 antibody (ab71977) at 1/500 dilution

    Lane 1 : CCNB1IP1 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    All lanes : Goat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

    Predicted band size: 32 kDa
    Observed band size: 28 kDa
    why is the actual band size different from the predicted?

References

This product has been referenced in:

  • Hu W  et al. MiR-373-3p enhances the chemosensitivity of gemcitabine through cell cycle pathway by targeting CCND2 in pancreatic carcinoma cells. Biomed Pharmacother 105:887-898 (2018). Read more (PubMed: 30021382) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab71977.
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