Key features and details
- Rabbit polyclonal to CCNDBP1
- Suitable for: ICC/IF, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-CCNDBP1 antibody
See all CCNDBP1 primary antibodies
DescriptionRabbit polyclonal to CCNDBP1
Tested applicationsSuitable for: ICC/IF, WBmore details
Species reactivityReacts with: Human
Predicted to work with: Cynomolgus monkey, Orangutan
- RT-4 cell lysate; A431 cells.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab220275 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 0.25 - 2 µg/ml.|
|WB||Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 40 kDa.|
FunctionMay negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
Tissue specificityUbiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
Sequence similaritiesBelongs to the CCNDBP1 family.
Developmental stageExpression may increase during differentiation.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- AU022347 antibody
- CCDB1_HUMAN antibody
- CCNDBP 1 antibody
ab220275 has been referenced in 1 publication.
- Tan C et al. Activation of PTGS2/NF-?B signaling pathway enhances radiation resistance of glioma. Cancer Med 8:1175-1185 (2019). PubMed: 30740906