Key features and details
- Rabbit polyclonal to CCNDBP1 - C-terminal
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-CCNDBP1 antibody - C-terminal
See all CCNDBP1 primary antibodies
DescriptionRabbit polyclonal to CCNDBP1 - C-terminal
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide, corresponding to a region within amino acids 298-360 of Human CCNDBP1 (Uniprot: O95273).
- CCNDBP1 transfected 293T cells; Human endometrial tissue.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab153964 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 40 kDa.|
|IHC-P||1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionMay negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
Tissue specificityUbiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
Sequence similaritiesBelongs to the CCNDBP1 family.
Developmental stageExpression may increase during differentiation.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- AU022347 antibody
- CCDB1_HUMAN antibody
- CCNDBP 1 antibody
All lanes : Anti-CCNDBP1 antibody - C-terminal (ab153964) at 1/500 dilution
Lane 1 : 293T lysate, non-transfected
Lane 2 : 293T lysate, transfected with CCNDBP1
Predicted band size: 40 kDa
12% SDS PAGE
Immunohistochemical analysis of paraffin-embedded Human endomitrial tissue labeling CCNDBP1 with ab153964 at 1/100 dilution.
ab153964 has not yet been referenced specifically in any publications.