Overview

  • Product name

  • Description

    Rabbit polyclonal to CCP5
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Cow, Giant Panda
  • Immunogen

    Recombinant fragment corresponding to Human CCP5 aa 150-235. H192R.
    Sequence:

    TTFFAFCYPFSYSDCQELLNQLDQRFPENHPTHSSPLDTIYYRRELLCYS LDGLRVDLLTITSCHGLREDREPRLEQLFPDTSTPR


    Database link: Q8NDL9

  • Positive control

    • IHC-P: Human testis tissue.
  • General notes

     This product was previously labelled as AGBL5

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.2
    Preservative: 0.02% Sodium azide
    Constituents: 40% Glycerol, PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab224138 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Metallocarboxypeptidase that mediates tubulin deglutamylation. Specifically catalyzes the deglutamylation of the branching point glutamate side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/ CCP1, AGBL1/CCP4 and AGBL4/CCP6.
  • Tissue specificity

    Expressed in brain.
  • Sequence similarities

    Belongs to the peptidase M14 family.
  • Cellular localization

    Cytoplasm > cytosol. Nucleus. Mainly cytoplasmic. Slight accumulation in the nucleus is observed.
  • Information by UniProt
  • Database links

  • Alternative names

    • AGBL5 antibody
    • ATP/GTP binding protein like 5 antibody
    • ATP/GTP-binding protein-like 5 antibody
    • CBPC5_HUMAN antibody
    • CCP5 antibody
    • Cytosolic carboxypeptidase like protein 5 antibody
    • Cytosolic carboxypeptidase-like protein 5 antibody
    • FLJ21839 antibody
    • Hypothetical protein FLJ21839 antibody
    see all

Images

  • Paraffin-embedded human testis tissue stained for CCP5 using ab224138 at 1/50 dilution in immunohistochemical analysis.

References

ab224138 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab224138.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up