Anti-CCR1 antibody (ab13240)
Key features and details
- Goat polyclonal to CCR1
- Suitable for: ELISA, ICC, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CCR1 antibody
See all CCR1 primary antibodies -
Description
Goat polyclonal to CCR1 -
Host species
Goat -
Specificity
Peptide sequence is < 50 % identical to other chemokine receptors in this region. -
Tested applications
Suitable for: ELISA, ICC, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Macaque monkeyDoes not react with: Mouse -
Immunogen
Synthetic peptide corresponding to Human CCR1 aa 7-24 (N terminal).
Sequence:TEDYDTTTEFDYGDATPC
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Positive control
- Immunocytochemistry on human peripheral blood leukocytes.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.1% Sodium azide
Constituents: PBS, 0.1% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab13240 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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ICC |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
ICC
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Function
Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. -
Tissue specificity
Widely expressed in different hematopoietic cells. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 1230 Human
- Entrez Gene: 574188 Macaque monkey
- Omim: 601159 Human
- SwissProt: P32246 Human
- Unigene: 301921 Human
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Alternative names
- C C chemokine receptor type 1 antibody
- C C CKR 1 antibody
- C-C chemokine receptor type 1 antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab13240 has been referenced in 1 publication.
- Sheng H et al. Knockdown of FOXP1 promotes the development of lung adenocarcinoma. Cancer Biol Ther 20:537-545 (2019). PubMed: 30409062