Overview

  • Product name

  • Description

    Goat polyclonal to CCR1
  • Host species

    Goat
  • Tested applications

    Suitable for: WB, IHC-P, ICCmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey
  • Immunogen

    Synthetic peptide:

    TEDYDTTTEFDYGDATPC

    , corresponding to the N terminal extracellular domain, of Human CCR1 (amino acids 7-24).

  • Positive control

    • Human spleen tissue

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituents: 99% PBS, 0.1% BSA
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab139399 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 41 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC 1/400.

Target

  • Function

    Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
  • Tissue specificity

    Widely expressed in different hematopoietic cells.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • C C chemokine receptor type 1 antibody
    • C C CKR 1 antibody
    • C-C chemokine receptor type 1 antibody
    • C-C CKR-1 antibody
    • CC CKR 1 antibody
    • CC-CKR-1 antibody
    • CCR 1 antibody
    • CCR-1 antibody
    • CCR1 antibody
    • CCR1_HUMAN antibody
    • CD 191 antibody
    • CD191 antibody
    • CD191 antigen antibody
    • Chemokine (C C motif) receptor 1 antibody
    • Chemokine C C motif receptor 1 antibody
    • CKR 1 antibody
    • CKR1 antibody
    • CMKBR 1 antibody
    • CMKBR1 antibody
    • CMKR 1 antibody
    • CMKR1 antibody
    • HM145 antibody
    • LD78 receptor antibody
    • Macrophage inflammatory protein 1 alpha /Rantes receptor antibody
    • Macrophage inflammatory protein 1 alpha receptor antibody
    • Macrophage inflammatory protein 1-alpha receptor antibody
    • Mip 1a R antibody
    • MIP 1alpha R antibody
    • MIP-1alpha-R antibody
    • MIP1aR antibody
    • RANTES R antibody
    • RANTES receptor antibody
    • RANTES-R antibody
    • SCYAR1 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin embedded Human spleen tissue labelling CCR1 with ab139399 at 5 µg/ml.

References

This product has been referenced in:

  • Liang Q  et al. TRIM47 is up-regulated in colorectal cancer, promoting ubiquitination and degradation of SMAD4. J Exp Clin Cancer Res 38:159 (2019). Read more (PubMed: 30979374) »
See 1 Publication for this product

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