Overview

  • Product name
  • Description
    Rabbit polyclonal to CCR1
  • Host species
    Rabbit
  • Specificity
    ab19013 recognises CCR1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human CCR1. Surrounding amino acid 341
    (Peptide available as ab185720)

  • Positive control
    • A357 cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Thimerosal (merthiolate)
    Constituents: PBS, 50% Glycerol, 1% BSA
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab19013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 4 µg/ml. Predicted molecular weight: 43 kDa.Can be blocked with CCR1 peptide (ab185720).

Target

  • Function
    Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
  • Tissue specificity
    Widely expressed in different hematopoietic cells.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C C chemokine receptor type 1 antibody
    • C C CKR 1 antibody
    • C-C chemokine receptor type 1 antibody
    • C-C CKR-1 antibody
    • CC CKR 1 antibody
    • CC-CKR-1 antibody
    • CCR 1 antibody
    • CCR-1 antibody
    • CCR1 antibody
    • CCR1_HUMAN antibody
    • CD 191 antibody
    • CD191 antibody
    • CD191 antigen antibody
    • Chemokine (C C motif) receptor 1 antibody
    • Chemokine C C motif receptor 1 antibody
    • CKR 1 antibody
    • CKR1 antibody
    • CMKBR 1 antibody
    • CMKBR1 antibody
    • CMKR 1 antibody
    • CMKR1 antibody
    • HM145 antibody
    • LD78 receptor antibody
    • Macrophage inflammatory protein 1 alpha /Rantes receptor antibody
    • Macrophage inflammatory protein 1 alpha receptor antibody
    • Macrophage inflammatory protein 1-alpha receptor antibody
    • Mip 1a R antibody
    • MIP 1alpha R antibody
    • MIP-1alpha-R antibody
    • MIP1aR antibody
    • RANTES R antibody
    • RANTES receptor antibody
    • RANTES-R antibody
    • SCYAR1 antibody
    see all

Images

  • Anti-CCR1 antibody (ab19013) at 1 µg/ml + A357 cell lysate

    Predicted band size: 43 kDa
    Observed band size: 43 kDa

References

This product has been referenced in:
  • Hyldahl RD  et al. Satellite cell activity is differentially affected by contraction mode in human muscle following a work-matched bout of exercise. Front Physiol 5:485 (2014). IHC . Read more (PubMed: 25566087) »
  • Barron DA  et al. TGF-ß1 Induces an Age-Dependent Inflammation of Nerve Ganglia and Fibroplasia in the Prostate Gland Stroma of a Novel Transgenic Mouse. PLoS One 5:e13751 (2010). IHC . Read more (PubMed: 21060787) »

See all 2 Publications for this product

Customer reviews and Q&As

Thank you for contacting us. Since the antibody was raised against the full length protein (Recombinant full length protein (Human): CCR1), and epitope mapping has not been performed - we do not have information about where the antibody binding site w...

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Thank you for contacting us for technical support and the protocol details, the image is very useful to understand the customer's problem. Is the customer using A357 cell lysate, not A375? This is a good positive control and ab19013 should work ver...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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