Anti-CCR1 antibody - N-terminal (ab140756)
Key features and details
- Rabbit polyclonal to CCR1 - N-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CCR1 antibody - N-terminal
See all CCR1 primary antibodies -
Description
Rabbit polyclonal to CCR1 - N-terminal -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Hamster, Monkey, Gorilla -
Immunogen
18 amino acid synthetic peptide from the N terminal extracellular domain of Human CCR1 (NP_001286.1).
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Positive control
- Human small intestine, vessel tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab140756 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P | (1) |
Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. -
Tissue specificity
Widely expressed in different hematopoietic cells. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 1230 Human
- Omim: 601159 Human
- SwissProt: P32246 Human
- Unigene: 301921 Human
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Alternative names
- C C chemokine receptor type 1 antibody
- C C CKR 1 antibody
- C-C chemokine receptor type 1 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab140756 has been referenced in 2 publications.
- Hirayama H et al. Expression of C-C motif chemokines and their receptors in bovine placentomes at spontaneous and induced parturition. J Reprod Dev 66:49-55 (2020). PubMed: 31761882
- Sakumoto R et al. Possible Roles of CC- and CXC-Chemokines in Regulating Bovine Endometrial Function during Early Pregnancy. Int J Mol Sci 18:N/A (2017). IHC-P ; Cow . PubMed: 28362325