Anti-CCR2 antibody - C-terminal (ab227015)
- Datasheet
- References (1)
- Protocols
Overview
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Product name
Anti-CCR2 antibody - C-terminal
See all CCR2 primary antibodies -
Description
Rabbit polyclonal to CCR2 - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Rat
Predicted to work with: Mouse
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Immunogen
Synthetic peptide within Mouse CCR2 aa 323-370 (C terminal) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: P51683 -
Positive control
- IHC-P: Rat liver and stomach tissues.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituents: 1% BSA, 50% Glycerol
Aqueous buffered solution -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab227015 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Post-translational
modificationsN-glycosylated. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 12772 Mouse
- Entrez Gene: 60463 Rat
- SwissProt: P51683 Mouse
- SwissProt: O55193 Rat
- Unigene: 6272 Mouse
- Unigene: 211983 Rat
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Alternative names
- C C chemokine receptor type 2 antibody
- C C CKR 2 antibody
- C-C chemokine receptor type 2 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR2 antibody - C-terminal (ab227015)PFA-fixed, paraffin-embedded rat stomach tissue stained for CCR2 using ab227015 at 1/400 dilution in immunohistochemical analysis. Detection: DAB staining.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR2 antibody - C-terminal (ab227015)PFA-fixed, paraffin-embedded rat liver tissue stained for CCR2 using ab227015 at 1/400 dilution in immunohistochemical analysis. Detection: DAB staining.
Datasheets and documents
References
This product has been referenced in:
- Li L et al. The Spleen Promotes the Secretion of CCL2 and Supports an M1 Dominant Phenotype in Hepatic Macrophages During Liver Fibrosis. Cell Physiol Biochem 51:557-574 (2018). Read more (PubMed: 30458454) »
