Anti-CCR3 antibody (ab25789)
- Datasheet
- References
- Protocols
Overview
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Product nameAnti-CCR3 antibody
See all CCR3 primary antibodies -
DescriptionGoat polyclonal to CCR3
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Host speciesGoat
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SpecificityThis antibody recognizes mouse CCR3 and the peptide sequence is < 50 % identical to other chemokine receptors in this region.
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Tested applicationsSuitable for: WB, ICC, IHC-Pmore details
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Species reactivityReacts with: Mouse
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Immunogen
Synthetic peptide:
TDEIKTVVESFETTPYEYEWAPPC
, corresponding to N terminal amino acids 5-29 of Mouse CCR3 -
Positive control
- Human spleen sections or cytosmears/cytospins of human peripheral blood leukocytes. A549 cell line also has been shown to express CCR3 receptor.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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Storage bufferpH: 7.20
Preservative: 0.1% Sodium azide
Constituents: 0.21% Potassium phosphate, 0.812% Sodium chloride, 0.1% BSA -
Concentration information loading... -
PurityProtein G purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab25789 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000. Predicted molecular weight: 43 kDa. | |
| ICC | 1/400. | |
| IHC-P | Use at an assay dependent dilution. |
Target
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FunctionReceptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
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Tissue specificityIn eosinophils as well as trace amounts in neutrophils and monocytes.
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Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
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Cellular localizationCell membrane.
- Information by UniProt
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Database links
- Entrez Gene: 12771 Mouse
- SwissProt: P51678 Mouse
- Unigene: 57050 Mouse
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Alternative names
- B chemokine receptor antibody
- b-chemokine receptor antibody
- C C chemokine receptor type 3 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR3 antibody (ab25789)Immunohistochemistry of CCR3 (ab25789) antibody to mouse CCR3 on paraffin section of mouse spleen.
Protocols
References
ab25789 has not yet been referenced specifically in any publications.
