Anti-CCR3 antibody (ab25789)
Key features and details
- Goat polyclonal to CCR3
- Suitable for: WB, ICC, IHC-P
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-CCR3 antibody
See all CCR3 primary antibodies -
Description
Goat polyclonal to CCR3 -
Host species
Goat -
Specificity
This antibody recognizes mouse CCR3 and the peptide sequence is < 50 % identical to other chemokine receptors in this region. -
Tested applications
Suitable for: WB, ICC, IHC-Pmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Synthetic peptide:
TDEIKTVVESFETTPYEYEWAPPC
, corresponding to N terminal amino acids 5-29 of Mouse CCR3 -
Positive control
- Human spleen sections or cytosmears/cytospins of human peripheral blood leukocytes. A549 cell line also has been shown to express CCR3 receptor.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.1% Sodium azide
Constituents: 0.21% Potassium phosphate, 0.812% Sodium chloride, 0.1% BSA -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab25789 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000. Predicted molecular weight: 43 kDa. | |
| ICC | 1/400. | |
| IHC-P | Use at an assay dependent dilution. |
Target
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Function
Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. -
Tissue specificity
In eosinophils as well as trace amounts in neutrophils and monocytes. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 12771 Mouse
- SwissProt: P51678 Mouse
- Unigene: 57050 Mouse
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Alternative names
- B chemokine receptor antibody
- b-chemokine receptor antibody
- C C chemokine receptor type 3 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR3 antibody (ab25789)Immunohistochemistry of CCR3 (ab25789) antibody to mouse CCR3 on paraffin section of mouse spleen.
Protocols
References
ab25789 has not yet been referenced specifically in any publications.
