Anti-CCR3 antibody - N-terminal (ab189346)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-CCR3 antibody - N-terminal
See all CCR3 primary antibodies -
Description
Goat polyclonal to CCR3 - N-terminal -
Host species
Goat -
Tested applications
Suitable for: ICC, WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat
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Immunogen
Synthetic peptide corresponding to Mouse CCR3 aa 5-28 (N terminal).
Sequence:TDEIKTVVESFETTPYEYEWAPPC
Database link: P51678 -
Positive control
- Human skin tissue
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituents: 0.21% Potassium phosphate, 0.81% Sodium chloride, 0.1% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab189346 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC | 1/200. | |
| WB | 1/500. Predicted molecular weight: 42 kDa. | |
| IHC-P | Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. -
Tissue specificity
In eosinophils as well as trace amounts in neutrophils and monocytes. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 1232 Human
- Entrez Gene: 12771 Mouse
- Entrez Gene: 117027 Rat
- Omim: 601268 Human
- SwissProt: P51677 Human
- SwissProt: P51678 Mouse
- SwissProt: O54814 Rat
- Unigene: 506190 Human
see all -
Alternative names
- B chemokine receptor antibody
- b-chemokine receptor antibody
- C C chemokine receptor type 3 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR3 antibody - N-terminal (ab189346)Immunohistochemical analysis of formalin-fixed paraffin-embedded Human skin tissue labeling CCR3 with ab189346 at 5 µg/ml.
Protocols
References
ab189346 has not yet been referenced specifically in any publications.
