Anti-CCR6 antibody (ab1659)
- Datasheet
- References (1)
- Protocols
Overview
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Product nameAnti-CCR6 antibody
See all CCR6 primary antibodies -
DescriptionGoat polyclonal to CCR6
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Host speciesGoat
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Tested applicationsSuitable for: IHC-Fr, ELISA, ICC, IHC-Pmore details
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Species reactivityReacts with: Human
Does not react with: Mouse -
Immunogen
Synthetic peptide:
YFVSVNTSYYSVDSEMLLCSLQEVRQFSR
, corresponding to amino acids 18-46 of Human CCR6. -
Positive control
- Human spleen or peripheral blood
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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Storage bufferPreservative: 0.1% Sodium azide
Constituent: 0.1% BSA -
Concentration information loading...
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PurityImmunogen affinity purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Alternative Products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab1659 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-Fr | 1/250. PubMed: 19095953 | |
ELISA | 1/75000. | |
ICC | 1/300. | |
IHC-P | 1/250. |
Target
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FunctionReceptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.
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Tissue specificitySpleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.
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Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
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Cellular localizationCell membrane.
- Information by UniProt
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Database links
- Entrez Gene: 1235 Human
- Omim: 601835 Human
- SwissProt: P51684 Human
- Unigene: 46468 Human
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Alternative names
- BN 1 antibody
- BN1 antibody
- C C chemokine receptor type 6 antibody
see all
Images
References
This product has been referenced in:
- Salim SY et al. CD83+CCR7- dendritic cells accumulate in the subepithelial dome and internalize translocated Escherichia coli HB101 in the Peyer's patches of ileal Crohn's disease. Am J Pathol 174:82-90 (2009). IHC-Fr ; Human . Read more (PubMed: 19095953) »