Product nameAnti-CCR7 antibody
See all CCR7 primary antibodies
DescriptionGoat polyclonal to CCR7
SpecificityPeptide sequence is < 50 % identical to other mouse chemokine receptors in this region. The antibody has been tested in an academic lab on cells transfected with CCR7 receptor, we do not have information regarding its use against endogenous protein.
Tested applicationsSuitable for: ELISA, Flow Cyt, IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
- IHC-P: Mouse spleen, human spleen. WB: cells transfected with CCR7 receptor
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: 0.1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab1657 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ab37373 - Goat polyclonal IgG, is suitable for use as an isotype control with this antibody.
|WB||1/1000. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).|
FunctionReceptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Tissue specificityExpressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- BLR 2 antibody
- BLR2 antibody
- C C chemokine receptor type 7 antibody
ab1657, at a dilution of 1/250, staining CCR7 in mouse spleen section by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
Anti-CCR7 antibody (ab1657) at 1 µg/ml + K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell Lysate at 10 µg
Rabbit polyclonal to Goat IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 43 kDa
Observed band size: 43 kDa
Exposure time: 20 minutes
This product has been referenced in:
- Salim SY et al. CD83+CCR7- dendritic cells accumulate in the subepithelial dome and internalize translocated Escherichia coli HB101 in the Peyer's patches of ileal Crohn's disease. Am J Pathol 174:82-90 (2009). IHC-P ; Human . Read more (PubMed: 19095953) »
- Pitkin L et al. Expression of CC chemokine receptor 7 in tonsillar cancer predicts cervical nodal metastasis, systemic relapse and survival. Br J Cancer 97:670-7 (2007). IHC-P ; Human . Read more (PubMed: 17687340) »