Key features and details
- Rabbit polyclonal to CCR7
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-CCR7 antibody
See all CCR7 primary antibodies
DescriptionRabbit polyclonal to CCR7
Specificityab191575 is predicted to not cross-react with other CCR proteins.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human CCR7 (internal sequence). (15 amino acid peptide; NP_001829).
Database link: P32248
- Human spleen tissue lysate; Human spleen tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab191575 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 - 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 43 kDa.|
FunctionReceptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Tissue specificityExpressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- BLR 2 antibody
- BLR2 antibody
- C C chemokine receptor type 7 antibody
Anti-CCR7 antibody (ab191575) at 1 µg/ml + Human spleen tissue lysate at 15 µg
Predicted band size: 43 kDa
Immunohistochemical analysis of paraffin-embedded Human spleen tissue labeling CCR7 with ab191575 at 5 µg/ml.
Immunohistochemical analysis of paraffin-embedded Human spleen tissue labeling CCR7 with ab191575 at 20 µg/ml.
ab191575 has been referenced in 3 publications.
- Chen S et al. Eluted 25-hydroxyvitamin D3 from radially aligned nanofiber scaffolds enhances cathelicidin production while reducing inflammatory response in human immune system-engrafted mice. Acta Biomater 97:187-199 (2019). PubMed: 31386930
- Zhao Y et al. The effects of CCR7 and related signaling pathways on Leishmania major -infected human dendritic cells. J Cell Physiol N/A:N/A (2018). PubMed: 30584667
- van Dijk RA et al. A change in inflammatory footprint precedes plaque instability: a systematic evaluation of cellular aspects of the adaptive immune response in human atherosclerosis. J Am Heart Assoc 4:N/A (2015). IHC-P ; Human . PubMed: 25814626