Overview

  • Product name
    Anti-CCR7 antibody - C-terminal
    See all CCR7 primary antibodies
  • Description
    Rabbit polyclonal to CCR7 - C-terminal
  • Host species
    Rabbit
  • Specificity
    BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except CXCR5 (65%).
  • Tested applications
    Suitable for: IHC-P, ICCmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Hamster, Cow, Dog, Turkey, Pig, Monkey, Zebrafish, Gorilla, Common marmoset, Bat, Elephant
  • Immunogen

    17 amino acid synthetic peptide from the C terminus of Human CCR7 (NP_001829.1).

  • Positive control
    • Human Tonsil and Spleen Tissue. CCR7 transfected cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab140758 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 14 µg/ml.
ICC Use a concentration of 14 µg/ml.

Target

  • Function
    Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
  • Tissue specificity
    Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • BLR 2 antibody
    • BLR2 antibody
    • C C chemokine receptor type 7 antibody
    • C C CKR 7 antibody
    • C-C chemokine receptor type 7 antibody
    • C-C CKR-7 antibody
    • CC chemokine receptor 7 antibody
    • CC chemokine receptor type 7 antibody
    • CC CKR 7 antibody
    • CC-CKR-7 antibody
    • CCCKR7 antibody
    • CCR 7 antibody
    • CCR-7 antibody
    • Ccr7 antibody
    • CCR7_HUMAN antibody
    • CD 197 antibody
    • CD197 antibody
    • CD197 antigen antibody
    • CDw197 antibody
    • Chemokine (C C motif) receptor 7 antibody
    • Chemokine (C C) receptor 7 antibody
    • Chemokine C C motif receptor 7 antibody
    • Chemokine C C receptor 7 antibody
    • Chemokine receptor 7 antibody
    • Chemokine receptor 7-like protein antibody
    • CMKBR7 antibody
    • EBI 1 antibody
    • EBI1 antibody
    • Ebi1h antibody
    • EBV Induced G Protein Coupled Receptor 1 antibody
    • EBV-induced G-protein coupled receptor 1 antibody
    • Epstein Barr virus induced G protein coupled receptor antibody
    • Epstein Barr virus induced gene 1 antibody
    • Epstein-Barr virus-induced G-protein coupled receptor 1 antibody
    • EVI 1 antibody
    • EVI1 antibody
    • Lymphocyte Specific G Protein Coupled Peptide Receptor antibody
    • MGC108519 antibody
    • MIP 3 beta receptor antibody
    • MIP-3 beta receptor antibody
    • MIP3 Beta Receptor antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue labelling CCR7 with ab140758 at 14 µg/ml.
  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human spleen tissue labelling CCR7 with ab140758 at 14 µg/ml.
  • Immunocytochemical analysis of CCR7 transfected cells (left) and a transfection control (right). The transfected cells show labelling of CCR7 with ab140758.

References

ab140758 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Filter by Application

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Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Pig Tissue sections (Small Intestine)
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: Dako Target Retrieval Buffer, pH 9
Specification
Small Intestine
Blocking step
Milk as blocking agent for 30 minute(s) · Concentration: 4% · Temperature: 23°C
Fixative
Formaldehyde

Ms. Alycia Cook

Verified customer

Submitted Jun 03 2015

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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