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    ccr7-antibody-c-terminal-ab140772.pdf

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Immunology Innate Immunity Chemokines Beta Chemokine Rec. (CCR)
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Anti-CCR7 antibody - C-terminal (ab140772)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR7 antibody - C-terminal (ab140772)

    Key features and details

    • Rabbit polyclonal to CCR7 - C-terminal
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

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    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

    View more associated products

    Overview

    • Product name

      Anti-CCR7 antibody - C-terminal
      See all CCR7 primary antibodies
    • Description

      Rabbit polyclonal to CCR7 - C-terminal
    • Host species

      Rabbit
    • Specificity

      BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
    • Tested applications

      Suitable for: IHC-Pmore details
    • Species reactivity

      Reacts with: Human
      Predicted to work with: Cow, Dog, Monkey, Gorilla, Common marmoset, Bat
    • Immunogen

      Synthetic 19 amino acid peptide from the C terminus of Human CCR7.

    • Positive control

      • Human lymph node tissue
    • General notes

      The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

      If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C.
    • Storage buffer

      Preservative: 0.1% Sodium azide
      Constituent: 99% PBS
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Immunology
      • Innate Immunity
      • Chemokines
      • Beta Chemokine Rec. (CCR)
      • Signal Transduction
      • Signaling Pathway
      • G Protein Signaling
      • GPCR

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

    Applications

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab140772 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    IHC-P
    Use a concentration of 6 - 8 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
    Notes
    IHC-P
    Use a concentration of 6 - 8 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    Target

    • Function

      Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
    • Tissue specificity

      Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family.
    • Cellular localization

      Cell membrane.
    • Target information above from: UniProt accession P32248 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 510668 Cow
      • Entrez Gene: 491011 Dog
      • Entrez Gene: 1236 Human
      • Omim: 600242 Human
      • SwissProt: Q5MD62 Cow
      • SwissProt: P32248 Human
      • Unigene: 370036 Human
      • Alternative names

        • BLR 2 antibody
        • BLR2 antibody
        • C C chemokine receptor type 7 antibody
        • C C CKR 7 antibody
        • C-C chemokine receptor type 7 antibody
        • C-C CKR-7 antibody
        • CC chemokine receptor 7 antibody
        • CC chemokine receptor type 7 antibody
        • CC CKR 7 antibody
        • CC-CKR-7 antibody
        • CCCKR7 antibody
        • CCR 7 antibody
        • CCR-7 antibody
        • Ccr7 antibody
        • CCR7_HUMAN antibody
        • CD 197 antibody
        • CD197 antibody
        • CD197 antigen antibody
        • CDw197 antibody
        • Chemokine (C C motif) receptor 7 antibody
        • Chemokine (C C) receptor 7 antibody
        • Chemokine C C motif receptor 7 antibody
        • Chemokine C C receptor 7 antibody
        • Chemokine receptor 7 antibody
        • Chemokine receptor 7-like protein antibody
        • CMKBR7 antibody
        • EBI 1 antibody
        • EBI1 antibody
        • Ebi1h antibody
        • EBV Induced G Protein Coupled Receptor 1 antibody
        • EBV-induced G-protein coupled receptor 1 antibody
        • Epstein Barr virus induced G protein coupled receptor antibody
        • Epstein Barr virus induced gene 1 antibody
        • Epstein-Barr virus-induced G-protein coupled receptor 1 antibody
        • EVI 1 antibody
        • EVI1 antibody
        • Lymphocyte Specific G Protein Coupled Peptide Receptor antibody
        • MGC108519 antibody
        • MIP 3 beta receptor antibody
        • MIP-3 beta receptor antibody
        • MIP3 Beta Receptor antibody
        see all

      Images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR7 antibody - C-terminal (ab140772)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR7 antibody - C-terminal (ab140772)
        Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human lymph node tissue labelling CCR7 with ab140772 at 8 µg/ml.

      Protocols

      • Immunohistochemistry protocols

      Click here to view the general protocols

      Datasheets and documents

      • SDS download

      • Datasheet download

        Download

      References (0)

      Publishing research using ab140772? Please let us know so that we can cite the reference in this datasheet.

      ab140772 has not yet been referenced specifically in any publications.

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