Recombinant Anti-CCR7 antibody [Y59] (ab32527)

Rabbit recombinant monoclonal CCR7 antibody [Y59]. Validated in WB, IP, ICC/IF and tested in Mouse, Rat, Human, Rhesus monkey. Cited in 29 publication(s). Independently reviewed in 12 review(s).

Publishing research using ab32527? Please let us know so that we can cite the reference in this datasheet.

ab32527 has been referenced in 32 publications.

  • Aussel A  et al. Cell and tissue responses at the interface with a chitosan hydrogel intended for vascular applications: in vitro and in vivo exploration. Biomed Mater 14:025009 (2019). PubMed: 30609413
  • Hsu M  et al. Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells. Nat Commun 10:229 (2019). PubMed: 30651548
  • Prest TA  et al. Nerve-specific, xenogeneic extracellular matrix hydrogel promotes recovery following peripheral nerve injury. J Biomed Mater Res A 106:450-459 (2018). PubMed: 28891122
  • Basheer HA  et al. Hypoxia modulates CCR7 expression in head and neck cancers. Oral Oncol 80:64-73 (2018). PubMed: 29706190
  • Wang L  et al. CCR7 regulates ANO6 to promote migration of pancreatic ductal adenocarcinoma cells via the ERK signaling pathway. Oncol Lett 16:2599-2605 (2018). PubMed: 30013654
  • Song N  et al. miR-21 Protects Against Ischemia/Reperfusion-Induced Acute Kidney Injury by Preventing Epithelial Cell Apoptosis and Inhibiting Dendritic Cell Maturation. Front Physiol 9:790 (2018). PubMed: 30013485
  • Zhong G  et al. Chemokine (C-C motif) ligand 21/C-C chemokine receptor type 7 triggers migration and invasion of human lung cancer cells by epithelial-mesenchymal transition via the extracellular signal-regulated kinase signaling pathway. Mol Med Rep 15:4100-4108 (2017). PubMed: 28487957
  • Luo Y  et al. Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis. Cell Res 27:352-372 (2017). PubMed: 28084332
  • Adisa AO  et al. Evaluation of Tumour Associated Macrophages and Angiogenesis in Ameloblastoma. J Clin Diagn Res 11:ZC33-ZC35 (2017). PubMed: 29207829
  • Kühne L  et al. Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy. BMC Immunol 18:52 (2017). PubMed: 29258420
  • Wu G  et al. Matrine alleviates lipopolysaccharide-induced intestinal inflammation and oxidative stress via CCR7 signal. Oncotarget 8:11621-11628 (2017). PubMed: 28086227
  • Lim JE  et al. A neuropeptide, Substance-P, directly induces tissue-repairing M2 like macrophages by activating the PI3K/Akt/mTOR pathway even in the presence of IFN?. Sci Rep 7:9417 (2017). PubMed: 28842601
  • Zhang L  et al. Inhibition of CCR7 promotes NF-?B-dependent apoptosis and suppresses epithelial-mesenchymal transition in non-small cell lung cancer. Oncol Rep 37:2913-2919 (2017). PubMed: 28339080
  • Xia Y  et al. Prognostic value of CC-chemokine receptor seven expression in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitor. BMC Cancer 17:70 (2017). PubMed: 28114889
  • Sonbul SN  et al. Chemokine (C-C motif) receptor 7 (CCR7) associates with the tumour immune microenvironment but not progression in invasive breast carcinoma. J Pathol Clin Res 3:105-114 (2017). WB ; Human . PubMed: 28451459
  • Subramanian S  et al. TREM-1 associated macrophage polarization plays a significant role in inducing insulin resistance in obese population. J Transl Med 15:85 (2017). IHC-P ; Human . PubMed: 28454543
  • Chen J  et al. CCR7 as a predictive biomarker associated with computed tomography for the diagnosis of lymph node metastasis in bladder carcinoma. Oncol Lett 11:735-740 (2016). PubMed: 26870276
  • Zhang L  et al. CCL21/CCR7 Axis Contributed to CD133+ Pancreatic Cancer Stem-Like Cell Metastasis via EMT and Erk/NF-?B Pathway. PLoS One 11:e0158529 (2016). PubMed: 27505247
  • Shi JY  et al. Naive Treg-like CCR7(+) mononuclear cells indicate unfavorable prognosis in hepatocellular carcinoma. Tumour Biol 37:9909-17 (2016). IF ; Human . PubMed: 26813566
  • Pang MF  et al. TGF-ß1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis. Oncogene N/A:N/A (2015). WB, IHC-P, IF ; Mouse, Human . PubMed: 25961925
  • Huang HL  et al. Targeting of TGF-ß-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer. Oncotarget 6:995-1007 (2015). PubMed: 25557171
  • Guo J  et al. Effect of CCR7, CXCR4 and VEGF-C on the lymph node metastasis of human pancreatic ductal adenocarcinoma. Oncol Lett 5:1572-1578 (2013). IHC-P ; Human . PubMed: 23761820
  • Hayashi E  et al. Distinct morphologic, phenotypic, and clinical-course characteristics of indolent peripheral T-cell lymphoma. Hum Pathol 44:1927-36 (2013). PubMed: 23706909
  • Vasconcelos DP  et al. Macrophage polarization following chitosan implantation. Biomaterials 34:9952-9 (2013). PubMed: 24074837
  • Milicevic NM  et al. Role of CCL19/21 and its possible signaling through CXCR3 in development of metallophilic macrophages in the mouse thymus. Histochem Cell Biol 135:593-601 (2011). IHC-P ; Mouse . PubMed: 21611855
  • Feig JE  et al. HDL promotes rapid atherosclerosis regression in mice and alters inflammatory properties of plaque monocyte-derived cells. Proc Natl Acad Sci U S A 108:7166-71 (2011). PubMed: 21482781
  • Emmett MS  et al. CCR7 mediates directed growth of melanomas towards lymphatics. Microcirculation 18:172-82 (2011). PubMed: 21166932
  • Rebhun RB  et al. Constitutive expression of the alpha4 integrin correlates with tumorigenicity and lymph node metastasis of the B16 murine melanoma. Neoplasia 12:173-82 (2010). PubMed: 20126475
  • Rey-Gallardo A  et al. Polysialylated neuropilin-2 enhances human dendritic cell migration through the basic C-terminal region of CCL21. Glycobiology 20:1139-46 (2010). WB ; Human . PubMed: 20488940
  • Matsumoto Y  et al. Expression of master regulators of helper T-cell differentiation in peripheral T-cell lymphoma, not otherwise specified, by immunohistochemical analysis. Am J Clin Pathol 133:281-90 (2010). PubMed: 20093238
  • Turnis ME  et al. IRAK-M removal counteracts dendritic cell vaccine deficits in migration and longevity. J Immunol 185:4223-32 (2010). WB ; Mouse . PubMed: 20817880
  • Gottfried-Blackmore A  et al. Acute in vivo exposure to interferon-gamma enables resident brain dendritic cells to become effective antigen presenting cells. Proc Natl Acad Sci U S A 106:20918-23 (2009). PubMed: 19906988

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