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Immunology Innate Immunity Chemokines Beta Chemokine Rec. (CCR)
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Anti-CCR8 antibody - C-terminal (ab140804)

  • Datasheet
  • SDS
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR8 antibody - C-terminal (ab140804)

    Key features and details

    • Rabbit polyclonal to CCR8 - C-terminal
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG

    You may also be interested in

    Protein
    Product image
    Recombinant Human CCR8 protein (ab158145)
    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

    View more associated products

    Overview

    • Product name

      Anti-CCR8 antibody - C-terminal
      See all CCR8 primary antibodies
    • Description

      Rabbit polyclonal to CCR8 - C-terminal
    • Host species

      Rabbit
    • Specificity

      BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
    • Tested applications

      Suitable for: IHC-Pmore details
    • Species reactivity

      Reacts with: Human
      Predicted to work with: Monkey, Gorilla
    • Immunogen

      Synthetic 19 amino acid peptide from the C terminus of Human CCR8.

    • Positive control

      • Human tonsil, germinal center tissue.
    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C.
    • Storage buffer

      Preservative: 0.1% Sodium azide
      Constituent: 99% PBS
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Immunology
      • Innate Immunity
      • Chemokines
      • Beta Chemokine Rec. (CCR)
      • Microbiology
      • Interspecies Interaction
      • Host Virus Interaction
      • Immunology
      • Immune System Diseases
      • Antiviral Signaling
      • HIV-related

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
    • Recombinant Protein

      • Recombinant Human CCR8 protein (ab158145)

    Applications

    Our Abpromise guarantee covers the use of ab140804 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    IHC-P Use a concentration of 22 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    Target

    • Function

      Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.
    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family.
    • Cellular localization

      Cell membrane.
    • Target information above from: UniProt accession P51685 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 1237 Human
      • Omim: 601834 Human
      • SwissProt: P51685 Human
      • Unigene: 113222 Human
      • Alternative names

        • C C chemokine receptor type 8 antibody
        • C C CKR 8 antibody
        • C C motif chemokine receptor 8 antibody
        • C-C chemokine receptor type 8 antibody
        • C-C CKR-8 antibody
        • CC chemokine receptor 8 antibody
        • CC chemokine receptor CHEMR1 antibody
        • CC chemokine receptor type 8 antibody
        • CC CKR 8 antibody
        • CC-CKR-8 antibody
        • CCR 8 antibody
        • CCR-8 antibody
        • Ccr8 antibody
        • CCR8 protein antibody
        • CCR8-L antibody
        • CCR8_HUMAN antibody
        • CDw198 antibody
        • CDw198 antigen antibody
        • Chemokine (C C motif) receptor 8 antibody
        • Chemokine (C C) receptor 8 antibody
        • Chemokine (C C) receptor like 2 antibody
        • Chemokine (CC motif) receptor 8 antibody
        • Chemokine (CC) receptor 8 antibody
        • Chemokine (CC) receptor like 1 antibody
        • Chemokine (CC) receptor like 2 antibody
        • Chemokine C C motif receptor 8 antibody
        • Chemokine C C receptor 8 antibody
        • Chemokine CC motif receptor 8 antibody
        • Chemokine CC receptor 8 antibody
        • Chemokine receptor 8 antibody
        • Chemokine receptor like 1 antibody
        • Chemokine receptor-like 1 antibody
        • CKR L1 antibody
        • CKR-L1 antibody
        • CKRL 1 antibody
        • CKRL1 antibody
        • CMKBR 8 antibody
        • CMKBR L2 antibody
        • CMKBR8 antibody
        • CMKBRL 2 antibody
        • CMKBRL2 antibody
        • CY 6 antibody
        • CY6 antibody
        • GPR CY6 antibody
        • GPR-CY6 antibody
        • GPRCY6 antibody
        • MGC123958 antibody
        • MGC123959 antibody
        • MGC129966 antibody
        • MGC129973 antibody
        • TER 1 antibody
        • TER1 antibody
        see all

      Images

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR8 antibody - C-terminal (ab140804)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CCR8 antibody - C-terminal (ab140804)
        Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil, germinal center tissue labelling CCR8 with ab140804 at 22 µg/ml.

      Protocols

      • Immunohistochemistry protocols

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet
      • SDS
    • References (0)

      Publishing research using ab140804? Please let us know so that we can cite the reference in this datasheet.

      ab140804 has not yet been referenced specifically in any publications.

      Customer reviews and Q&As

      Show All Reviews Q&A
      Submit a review Submit a question

      Question

      We have been using Annexin V-PE kit (ab14155) and run out of the binding buffer. Is the buffer in this kit sold separately? Does your product annexin V 10X binding buffer (ab140804) work with this kit? We appreciate your help if you could respond it ASAP. Our experiment has been set up and we are waiting for the buffer.

      Read More

      Abcam community

      Verified customer

      Asked on May 02 2006

      Answer

      Thank you for your enquiry. Yes, ab14084 is the replacement buffer product for this kit. I hope this information helps, please do not hesitate to contact us if you need any more advice or information.

      Read More

      Abcam Scientific Support

      Answered on May 02 2006

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com

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