Recombinant Anti-CCR8 antibody [EPR23744-160] (ab259792)
![Flow Cytometry - Anti-CCR8 antibody [EPR23744-160] (ab259792)](https://www.abcam.com/ps/products/259/ab259792/Images/ab259792-450311-anti-ccr8-antibody-epr23744160-flow-cytometry-human-peripheral-blood-mononuclear-cell.jpg "Flow Cytometry - Anti-CCR8 antibody [EPR23744-160] (ab259792)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR23744-160] to CCR8
- Suitable for: Flow Cyt
- Reacts with: Human
Overview
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Product name
Anti-CCR8 antibody [EPR23744-160]
See all CCR8 primary antibodies -
Description
Rabbit monoclonal [EPR23744-160] to CCR8 -
Host species
Rabbit -
Tested applications
Suitable for: Flow Cytmore details
Unsuitable for: ICC,IHC-P,IP or WB -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide within Human CCR8 aa 1-100. The exact sequence is proprietary.
Database link: P51685 -
Positive control
- Flow Cyt: Human peripheral blood mononuclear cell.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 59.94% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR23744-160 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab259792 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | 1/500. |
Target
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Function
Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 1237 Human
- Omim: 601834 Human
- SwissProt: P51685 Human
- Unigene: 113222 Human
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Alternative names
- C C chemokine receptor type 8 antibody
- C C CKR 8 antibody
- C C motif chemokine receptor 8 antibody
see all
Images
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Flow Cytometry - Anti-CCR8 antibody [EPR23744-160] (ab259792)
Flow cytometric analysis of human peripheral blood mononuclear cell (PBMC) cells labelling CCR8 with ab259792 at 1/500 dilution (0.1µg)/ Right compared with a Rabbit monoclonal IgG (ab172730) / Left isotype control.
Goat anti rabbit IgG (Alexa Fluor® 488, ab150077) at 1/2000 dilution was used as the secondary antibody. Cells were stained with rabbit IgG or ab259792. Then stained with anti-CD4 conjugated to Alexa Fluor® 647.
Gated on viable cells.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
Certificate of Compliance
References (0)
ab259792 has not yet been referenced specifically in any publications.
