Overview

  • Product name

    Anti-CCRK antibody [EPR7338(2)]
    See all CCRK primary antibodies
  • Description

    Rabbit monoclonal [EPR7338(2)] to CCRK
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human CCRK aa 250-350. The exact sequence is proprietary.

  • Positive control

    • HepG2 and HCT-116 cell lysates
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab138494 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 39 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function

      Required for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
    • Sequence similarities

      Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
      Contains 1 protein kinase domain.
    • Cellular localization

      Nucleus. Cytoplasm. Cell projection > cilium.
    • Information by UniProt
    • Database links

    • Alternative names

      • CAK kinase p42 antibody
      • CAK-kinase p42 antibody
      • CCRK antibody
      • CDCH antibody
      • CDK activating kinase p42 antibody
      • CDK-activating kinase p42 antibody
      • cdk20 antibody
      • CDK20_HUMAN antibody
      • Cell cycle related kinase antibody
      • Cell cycle-related kinase antibody
      • Cell division protein kinase 20 antibody
      • Cyclin dependent protein kinase H antibody
      • Cyclin kinase activating kinase p42 antibody
      • Cyclin-dependent kinase 20 antibody
      • Cyclin-dependent protein kinase H antibody
      • Cyclin-kinase-activating kinase p42 antibody
      • p42 antibody
      • PNQALRE antibody
      see all

    Images

    • All lanes : Anti-CCRK antibody [EPR7338(2)] (ab138494) at 1/1000 dilution

      Lane 1 : HepG2 cell lysate
      Lane 2 : HCT-116 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 39 kDa

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    ab138494 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab138494.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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