Anti-CCXCR1/XCR1 antibody - Cytoplasmic domain (ab188896)
Key features and details
- Rabbit polyclonal to CCXCR1/XCR1 - Cytoplasmic domain
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CCXCR1/XCR1 antibody - Cytoplasmic domain -
Description
Rabbit polyclonal to CCXCR1/XCR1 - Cytoplasmic domain -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rabbit, Horse, Monkey, Gorilla, Common marmoset -
Immunogen
Synthetic peptide corresponding to Human CCXCR1/XCR1. Second cytoplasmic domain. 19 amino acid peptide.
Database link: P46094 -
Positive control
- Human tonsil tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab188896 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 100397333 Common marmoset
- Entrez Gene: 101148758 Gorilla
- Entrez Gene: 100065485 Horse
- Entrez Gene: 2829 Human
- Entrez Gene: 100352332 Rabbit
- Omim: 600552 Human
- SwissProt: P46094 Human
- Unigene: 248116 Human
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Alternative names
- CCXCR 1 antibody
- Chemokine (C motif) receptor 1 antibody
- Chemokine (C motif) XC receptor 1 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab188896 has been referenced in 1 publication.
- Zychowska M et al. Microglial Inhibition Influences XCL1/XCR1 Expression and Causes Analgesic Effects in a Mouse Model of Diabetic Neuropathy. Anesthesiology 125:573-89 (2016). PubMed: 27387353