Overview

  • Product name

    Anti-CD101 antibody [BB27] (Phycoerythrin)
    See all CD101 primary antibodies
  • Description

    Mouse monoclonal [BB27] to CD101 (Phycoerythrin)
  • Host species

    Mouse
  • Conjugation

    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to Human CD101. Human thymic clone B12.

  • Positive control

    • Flow cytometry: Human peripheral blood cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C. Do Not Freeze.
  • Storage buffer

    Preservative: 0.0975% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Size exclusion
  • Clonality

    Monoclonal
  • Clone number

    BB27
  • Isotype

    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab234248 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 10µl for 106 cells.

Target

  • Relevance

    CD101 is a disulfide-linked homodimeric type 1 glycoprotein. The peptide is comprised of 7 extracellular V-type IgSF domains. CD101 is highly expressed on monocytes, granulocytes, mucosal T cells, and on activated peripheral blood T cells. Expression is weak on resting T and B and NK cells, absent from platelets and weak or absent from most hematopoietic cell lines. CD101 is thought to play a co-stimulatory role in TCR/CD3-mediated T cell activation. Monoclonal antibodies against CD101 inhibit allogeneic T cell responses. Studies suggest that CD101 plays a major role in the activation of T cells by skin dendritic cells.
  • Cellular localization

    Cell Membrane
  • Database links

  • Alternative names

    • CD101 molecule antibody
    • cell surface glycoprotein V7 antibody
    • EWI-101 antibody
    • glu-Trp-Ile EWI motif-containing protein 101 antibody
    • IGSF2 antibody
    • Immunoglobulin superfamily member 2 antibody
    • Leukocyte surface protein antibody
    • V7 antibody
    • V7 LSB antibody
    see all

Images

  • Flow cytometric analysis of human peripheral blood cells labeling CD101 using ab234248. Surface staining, gated on leukocytes.

References

ab234248 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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