Overview

  • Product name

    Anti-CD103 antibody [2E7] (Biotin)
    See all CD103 primary antibodies
  • Description

    Armenian hamster monoclonal [2E7] to CD103 (Biotin)
  • Host species

    Armenian hamster
  • Conjugation

    Biotin
  • Specificity

    ab25211 recognises CD103/aIELß7 integrin complex.
  • Tested applications

    Suitable for: Flow Cyt, IHC-Fr, IPmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

Properties

Applications

Our Abpromise guarantee covers the use of ab25211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
IHC-Fr
IP
  • Application notes
    Flow Cyt: Use at an assay dependent dilution. Use up to 1ug/106 cells.
    IHC-Fr: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.
    In vivo activation: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
    • Tissue specificity

      Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
    • Sequence similarities

      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.
    • Domain

      The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    • Cellular localization

      Membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • A530055J10 antibody
      • alpha-E1 antibody
      • alpha-M290 antibody
      • aM290 antibody
      • Antigen CD103 antibody
      • CD 103 antibody
      • CD103 antibody
      • CD103 antigen antibody
      • HML 1 antigen antibody
      • HML-1 antigen antibody
      • HML1 antigen antibody
      • Human mucosal lymphocyte antigen 1 antibody
      • Human mucosal lymphocyte antigen 1, alpha subunit antibody
      • Huminae antibody
      • Integrin alpha E antibody
      • Integrin alpha E heavy chain antibody
      • Integrin alpha E light chain antibody
      • Integrin alpha E, epithelial-associated antibody
      • Integrin alpha E1 antibody
      • Integrin alpha IEL antibody
      • Integrin alpha M290 antibody
      • Integrin alpha-E heavy chain antibody
      • Integrin alpha-IEL antibody
      • Integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) antibody
      • Integrin, alpha E antibody
      • ITAE_HUMAN antibody
      • Itgae antibody
      • MGC141996 antibody
      • MGC183601 antibody
      • Mucosal lymphocyte 1 antigen antibody
      • Mucosal lymphocyte antigen 1 antibody
      see all

    Images

    • BALB/c mesenteric lymph node cells were first labeled with ab25211 at 0.1 µg/106 cells, and then double-stained with streptavidin-FITC and rat anti-mouse CD8a-R-PE (ab25498).  Small lymphocytes were gated and analyzed on a FACScan flow cytometer  (BDIS, San Jose, CA). 

    References

    This product has been referenced in:

    • Lefrançois L  et al. Developmental expression of the alpha IEL beta 7 integrin on T cell receptor gamma delta and T cell receptor alpha beta T cells. Eur J Immunol 24:635-40 (1994). Read more (PubMed: 7907296) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab25211.
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