Key features and details
- Armenian hamster monoclonal [2E7] to CD103 (Biotin)
- Suitable for: Flow Cyt, IHC-Fr, IP
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG
Product nameAnti-CD103 antibody [2E7] (Biotin)
See all CD103 primary antibodies
DescriptionArmenian hamster monoclonal [2E7] to CD103 (Biotin)
Host speciesArmenian hamster
Specificityab25211 recognises CD103/aIELß7 integrin complex.
Tested applicationsSuitable for: Flow Cyt, IHC-Fr, IPmore details
Species reactivityReacts with: Mouse
The details of the immunogen for this antibody are not available.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium azide
Concentration information loading...
Our Abpromise guarantee covers the use of ab25211 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
In vivo activation: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionIntegrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
Tissue specificityExpressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
Sequence similaritiesBelongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain.
DomainThe integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
- Information by UniProt
- A530055J10 antibody
- alpha-E1 antibody
- alpha-M290 antibody
BALB/c mesenteric lymph node cells were first labeled with ab25211 at 0.1 µg/106 cells, and then double-stained with streptavidin-FITC and rat anti-mouse CD8a-R-PE (ab25498). Small lymphocytes were gated and analyzed on a FACScan flow cytometer (BDIS, San Jose, CA).
ab25211 has been referenced in 1 publication.
- Lefrançois L et al. Developmental expression of the alpha IEL beta 7 integrin on T cell receptor gamma delta and T cell receptor alpha beta T cells. Eur J Immunol 24:635-40 (1994). PubMed: 7907296