Overview

  • Product name

    Anti-CD103 antibody [EPR4166]
    See all CD103 primary antibodies
  • Description

    Rabbit monoclonal [EPR4166] to CD103
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human CD103 aa 1-100. Corresponding to the extracellular domain and light chain

  • Positive control

    • HuT-78, Jurkat, 431, HeLa and K562 cell lysates.
  • General notes

    A trial size is available to purchase for this antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Clone EPR4166 is different from clone EPR4166(2).

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab108503 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 150 kDa (predicted molecular weight: 130 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function

      Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
    • Tissue specificity

      Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
    • Sequence similarities

      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.
    • Domain

      The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    • Cellular localization

      Membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • A530055J10 antibody
      • alpha-E1 antibody
      • alpha-M290 antibody
      • aM290 antibody
      • Antigen CD103 antibody
      • CD 103 antibody
      • CD103 antibody
      • CD103 antigen antibody
      • HML 1 antigen antibody
      • HML-1 antigen antibody
      • HML1 antigen antibody
      • Human mucosal lymphocyte antigen 1 antibody
      • Human mucosal lymphocyte antigen 1, alpha subunit antibody
      • Huminae antibody
      • Integrin alpha E antibody
      • Integrin alpha E heavy chain antibody
      • Integrin alpha E light chain antibody
      • Integrin alpha E, epithelial-associated antibody
      • Integrin alpha E1 antibody
      • Integrin alpha IEL antibody
      • Integrin alpha M290 antibody
      • Integrin alpha-E heavy chain antibody
      • Integrin alpha-IEL antibody
      • Integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) antibody
      • Integrin, alpha E antibody
      • ITAE_HUMAN antibody
      • Itgae antibody
      • MGC141996 antibody
      • MGC183601 antibody
      • Mucosal lymphocyte 1 antigen antibody
      • Mucosal lymphocyte antigen 1 antibody
      see all

    Images

    • All lanes : Anti-CD103 antibody [EPR4166] (ab108503) at 1/1000 dilution

      Lane 1 : HuT-78 cell lysate
      Lane 2 : Jurkat cell lysate
      Lane 3 : A431 cell lysate
      Lane 4 : HeLa cell lysate
      Lane 5 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 130 kDa
      Observed band size: 150 kDa
      why is the actual band size different from the predicted?

    References

    This product has been referenced in:

    • Ishibashi H  et al. Endoscopic and clinicopathological characteristics of gastrointestinal adult T-cell leukemia/lymphoma. J Gastrointest Oncol 10:723-733 (2019). Read more (PubMed: 31392053) »
    • Ishibashi H  et al. Multiple lesions of gastrointestinal tract invasion by monomorphic epitheliotropic intestinal T-cell lymphoma, accompanied by duodenal and intestinal enteropathy-like lesions and microscopic lymphocytic proctocolitis: a case series. Diagn Pathol 11:66 (2016). IHC-P ; Human . Read more (PubMed: 27457239) »
    See all 2 Publications for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab108503.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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