Overview

  • Product name
    Anti-CD105 antibody [2H6F11] (PerCP)
    See all CD105 primary antibodies
  • Description
    Mouse monoclonal [2H6F11] to CD105 (PerCP)
  • Host species
    Mouse
  • Conjugation
    PerCP. Ex: 482nm, Em: 675nm
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Partially purified cell membrane antigens from fresh leukaemia cells

  • Positive control
    • PMA-trated (72 hours) U-937 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab91138 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 20µl for 106 cells.

ab118658 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

Target

  • Function
    Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
  • Tissue specificity
    Endoglin is restricted to endothelial cells in all tissues except bone marrow.
  • Involvement in disease
    Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI528660 antibody
    • AI662476 antibody
    • CD 105 antibody
    • CD105 antibody
    • CD105 antigen antibody
    • EGLN_HUMAN antibody
    • END antibody
    • Endoglin antibody
    • Eng antibody
    • FLJ41744 antibody
    • HHT1 antibody
    • ORW antibody
    • ORW1 antibody
    • Osler Rendu Weber syndrome 1 antibody
    • RP11 228B15.2 antibody
    • S-endoglin antibody
    • SN6 antibody
    see all

References

This product has been referenced in:
  • Shi Q  et al. Differentiation of human umbilical cord Wharton's jelly-derived mesenchymal stem cells into endometrial cells. Stem Cell Res Ther 8:246 (2017). Read more (PubMed: 29096715) »
See 1 Publication for this product

Customer reviews and Q&As

Answer

Thank you for your enquiry.

I can confirm that as long as the flow cytometer usedhas the correct filters to excite and detectemission at the correct wavelength for the conjugated fluorophore, it will be compatible. I also looked up the technical specifications for this flow cytometer, and the filters it comes with are useable for detection of PerCP. However, you may want to check the filters your machine has are suitable, in case these have been changed at all:

The PerCP conjugate has excitation and emission at 477nm and 678nm.

The antibody has also been tested and therefore guaranteed for use in flow cytometry.

The price is available on the datasheet. Ensure to select the correct country (Poland) in the top right corner of the page, and it should then show the correct price:

ab91138 100 tests ####
Freight/Packing: ### to Poland

I hope this will be helpful to you. If you have any further questions, please do not hesitate to contact us.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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