Key features and details
- Mouse monoclonal [MEM226] to CD105, prediluted (Alexa Fluor® 488)
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: Alexa Fluor® 488. Ex: 495nm, Em: 519nm
- Isotype: IgG2a
Product nameAnti-CD105 antibody [MEM226], prediluted (Alexa Fluor® 488)
See all CD105 primary antibodies
DescriptionMouse monoclonal [MEM226] to CD105, prediluted (Alexa Fluor® 488)
ConjugationAlexa Fluor® 488. Ex: 495nm, Em: 519nm
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Human
Recombinant full length protein corresponding to Human CD105. Human CD105 cDNA was expressed in recombinant Vaccinia virus.
Database link: P17813
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at +4°C. Store In the Dark.
Storage bufferPreservative: 0.097% Sodium azide
Constituents: 99% PBS, 0.2% BSA
Concentration information loading...
Purification notesab187575 is conjugated with Alexa Fluor® 488 under optimum conditions and the conjugate purified by size-exclusion chromatography and adjusted for direct use.
Our Abpromise guarantee covers the use of ab187575 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 4µl for 106 cells.
Use 4 µl for 100 µl of Human whole blood cells in suspension.
ab171464 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
FunctionMajor glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
Tissue specificityEndoglin is restricted to endothelial cells in all tissues except bone marrow.
Involvement in diseaseDefects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
- Information by UniProt
- AI528660 antibody
- AI662476 antibody
- CD 105 antibody
ab187575 has not yet been referenced specifically in any publications.