Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 50% Glycerol, 0.01% BSA
Aqueous buffered solution
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab203588 in the following tested applications.
|WB||1/100 - 1/1000. Predicted molecular weight: 162 kDa.|
|IHC-P||1/100 - 1/500.
When using a fluorescent probe the recommended dilution is 1/50 – 1/200.
FunctionModulates negatively TGFB1 signaling in keratinocytes.
Tissue specificityWidely expressed with high level in uterus, aorta, heart, lung, trachea, placenta and in fetal heart, kidney, liver, spleen and lung. Expressed by CD34(+) acute myeloid leukemia cell lines, T-cell lines, activated T-lymphoblasts, endothelial cells and activated platelets. Isoform 5 is expressed in placenta. Isoform 1 is expressed in keratinocytes and placenta.
Sequence similaritiesBelongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
2 forms of 150 (p150) and 120 kDa (p120) exist due to proteolytic degradation from a 180 kDa form.
Cellular localizationCell membrane.
- Information by UniProt
- 150 KDa TGF beta 1 binding protein antibody
- 150 KDa TGF-beta-1-binding protein antibody
- 7D1 antibody
ab203588 has not yet been referenced specifically in any publications.