Product nameAnti-CD11a antibody 
See all CD11a primary antibodies
DescriptionMouse monoclonal  to CD11a
Tested applicationsSuitable for: Flow Cyt, IHC-Fr, IP, ICC/IF, Functional Studiesmore details
Species reactivityReacts with: Human
The details of the immunogen for this antibody are not available.
- Human peripheral blood lymphocytes.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Concentration information loading...
PurityProtein G purified
Purification notesThis antibody was purified from tissue culture supernatant.
Our Abpromise guarantee covers the use of ab34214 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||1/50 - 1/100.
ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
|IHC-Fr||Use at an assay dependent concentration.|
|IP||Use at an assay dependent concentration.|
|ICC/IF||Use at an assay dependent concentration.|
|Functional Studies||Use at an assay dependent concentration.|
FunctionIntegrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
Sequence similaritiesBelongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain.
DomainThe integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
- Information by UniProt
- Lymphocyte function associated antigen, type 1, alpha subunit antibody
- Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody
- Antigen CD11A antibody
This product has been referenced in:
- Levy O et al. Critical role of the complement system in group B streptococcus-induced tumor necrosis factor alpha release. Infect Immun 71:6344-53 (2003). Read more (PubMed: 14573654) »
- Demetter P et al. Increase in lymphoid follicles and leukocyte adhesion molecules emphasizes a role for the gut in spondyloarthropathy pathogenesis. J Pathol 198:517-22 (2002). Read more (PubMed: 12434422) »