Product nameAnti-CD11a antibody
See all CD11a primary antibodies
DescriptionRabbit polyclonal to CD11a
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Human
Recombinant fragment within Human CD11a. The exact sequence is proprietary.
Database link: P20701
- Jurkat, A549, Sw620, Raji, HO-8910, HepG2, U937 or Mouse spleen lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.3
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab186873 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 129 kDa.|
|IHC-P||1/50 - 1/200.
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
FunctionIntegrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
Sequence similaritiesBelongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain.
DomainThe integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
- Information by UniProt
- Lymphocyte function associated antigen, type 1, alpha subunit antibody
- Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody
- Antigen CD11A antibody
Lanes 1 & 3 : Anti-CD11a antibody (ab186873) at 1/1000 dilution
Lane 2 : Anti-CD11a antibody (ab186873)
Lane 1 : Jurkat cells
Lane 2 : HepG2 cells
Lane 3 : Mouse liver cells
Lysates/proteins at 40 µg per lane.
Predicted band size: 129 kDa
Western blot labeling CD11a with ab186873. Blocked with 5% nonfat milk.
This product has been referenced in:
- Tang TT et al. Employing Macrophage-Derived Microvesicle for Kidney-Targeted Delivery of Dexamethasone: An Efficient Therapeutic Strategy against Renal Inflammation and Fibrosis. Theranostics 9:4740-4755 (2019). Read more (PubMed: 31367254) »