Overview

  • Product name

    Anti-CD11c antibody [N418] - Low endotoxin, Azide free
    See all CD11c primary antibodies
  • Description

    Armenian Hamster monoclonal [N418] to CD11c - Low endotoxin, Azide free
  • Host species

    Armenian hamster
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Other Immunogen Type corresponding to Mouse CD11c. Mouse spleen dendritic cells

  • Positive control

    • Mouse C57Bl/6 splenocytes.
  • General notes

    Endotoxin Level: Less than 0.001 ng/ug antibody, as determined by the LAL assay.

Properties

Applications

Our Abpromise guarantee covers the use of ab185783 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 1µg for 105-8 cells.

In a final volume of 100 μL.

 

 

 

 

ab18479 - Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

Target

  • Function

    Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
  • Tissue specificity

    Predominantly expressed in monocytes and granulocytes.
  • Sequence similarities

    Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    Contains 1 VWFA domain.
  • Domain

    The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 95 alpha chain antibody
    • 95 antibody
    • CD 11c antibody
    • CD11 antigen like family member C antibody
    • CD11 antigen-like family member C antibody
    • CD11c antibody
    • CD11c antigen antibody
    • Complement component 3 receptor 4 subunit antibody
    • CR4 antibody
    • Integrin alpha X antibody
    • Integrin alpha X chain antibody
    • Integrin alpha-X antibody
    • Integrin aX antibody
    • Integrin subunit alpha X antibody
    • integrin, alpha X (antigen CD11C (p150), alpha polypeptide) antibody
    • integrin, alpha X (complement component 3 receptor 4 subunit antibody
    • ITAX_HUMAN antibody
    • ITGAX antibody
    • LEU M5 alpha subunit antibody
    • Leu M5 antibody
    • Leukocyte adhesion glycoprotein p150 95 alpha chain antibody
    • Leukocyte adhesion glycoprotein p150 antibody
    • Leukocyte adhesion receptor p150 95 antibody
    • Leukocyte adhesion receptor p150 antibody
    • Leukocyte surface antigen p150 95 alpha subunit antibody
    • Leukocyte surface antigen p150 alpha subunit antibody
    • Myeloid membrane antigen alpha subunit antibody
    • p150 95 integrin alpha chain antibody
    • p150 antibody
    • p150/95 antibody
    • SLEB6 antibody
    see all

Images

  • Flow cytometric analysis of mouse C57BI/6 splenocytes with an anti-Human/mouse CD45R antibody and 0.5 µg of armenian hamster IgG Isotype Control (left) or 0.5 µg of ab185783 (right) followed by anti-armenian hamster IgG FITC. Cells in the lymphocyte gate were used for analysis.

References

ab185783 has not yet been referenced specifically in any publications.

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