Anti-CD11+CD18 antibody [CVS 9] (ab23917)

Product name

Anti-CD11+CD18 antibody [CVS 9]
See all CD11+CD18 primary antibodies
Description

Mouse monoclonal [CVS 9] to CD11+CD18
Host species

Mouse
Specificity

This antibody recognises the equine CD11a/CD18 cell surface antigen, expressed by all equine leucocytes.
Tested applications

Suitable for: IHC-Fr, Flow Cytmore details
Species reactivity

Reacts with: Horse
Immunogen

Tissue/ cell preparation. Leuocytes (Horse).

Form

Liquid
Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer

Preservative: 0.01% Sodium azide
Constituent: Tissue culture supernatant
Purity

Tissue culture supernatant
Clonality

Monoclonal
Clone number

CVS 9
Myeloma

P3x63-Ag8.653
Isotype

IgG1
Research areas

Compatible Secondaries
- Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
- Goat Anti-Mouse IgG H&L (HRP) (ab205719)
Isotype control
- Mouse IgG1, kappa monoclonal [15-6E10A7] - Isotype Control (ab170190)

Our Abpromise guarantee covers the use of ab23917 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application	Abreviews	Notes
IHC-Fr		1/1.
Flow Cyt		Use at an assay dependent concentration. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Function

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
Tissue specificity

Leukocytes.
Sequence similarities

Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain.
Domain

The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
Cellular localization

Membrane.
Target information above from: UniProt accession P20701 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 100056128 Horse
- Entrez Gene: 100064803 Horse
- Entrez Gene: 100065508 Horse
Alternative names
- Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody
- CD11 antigen-like family member A antibody
- CD11a antibody
- CD18 antibody
- CR3 antibody
- Integrin alpha-L antibody
- Integrin beta 2 antibody
- Integrin gene promoter antibody
- ITAL_HUMAN antibody
- Itgal antibody
- ITGAM antibody
- ITGB2 antibody
- LAD antibody
- Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody
- Leukocyte function-associated molecule 1 alpha chain antibody
- LFA 1 alpha antibody
- LFA 1 antibody
- LFA-1A antibody
- LFA1 antibody
- LFA1A antibody
- Lymphocyte function associated antigen 1 antibody
- MAC1 antibody
- MFI7 antibody
- MO1A antibody
see all

Datasheet

Flow cytometry protocols
Immunohistochemistry protocols

ab23917 has not yet been referenced specifically in any publications.

Publishing research using ab23917? Please let us know so that we can cite the reference in this datasheet.

Location selector

Your location is currently set to:

Partner with us

Anti-CD11+CD18 antibody [CVS 9] (ab23917)

Overview

Properties

Associated products

Applications

Target

Datasheets and documents

Protocols

References

Customer reviews and Q&As