Overview

  • Product name
    Anti-CD11+CD18 antibody [CVS 9]
    See all CD11+CD18 primary antibodies
  • Description
    Mouse monoclonal [CVS 9] to CD11+CD18
  • Host species
    Mouse
  • Specificity
    This antibody recognises the equine CD11a/CD18 cell surface antigen, expressed by all equine leucocytes.
  • Tested applications
    Suitable for: IHC-Fr, Flow Cytmore details
  • Species reactivity
    Reacts with: Horse
  • Immunogen

    Tissue/ cell preparation. Leuocytes (Horse).

Properties

Applications

Our Abpromise guarantee covers the use of ab23917 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/1.
Flow Cyt Use at an assay dependent concentration.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
  • Tissue specificity
    Leukocytes.
  • Sequence similarities
    Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    Contains 1 VWFA domain.
  • Domain
    The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody
      • CD11 antigen-like family member A antibody
      • CD11a antibody
      • CD18 antibody
      • CR3 antibody
      • Integrin alpha-L antibody
      • Integrin beta 2 antibody
      • Integrin gene promoter antibody
      • ITAL_HUMAN antibody
      • Itgal antibody
      • ITGAM antibody
      • ITGB2 antibody
      • LAD antibody
      • Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody
      • Leukocyte function-associated molecule 1 alpha chain antibody
      • LFA 1 alpha antibody
      • LFA 1 antibody
      • LFA-1A antibody
      • LFA1 antibody
      • LFA1A antibody
      • Lymphocyte function associated antigen 1 antibody
      • MAC1 antibody
      • MFI7 antibody
      • MO1A antibody
      see all

    References

    ab23917 has not yet been referenced specifically in any publications.

    Publishing research using ab23917? Please let us know so that we can cite the reference in this datasheet.

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