Overview

  • Product name

  • Description

    Rabbit polyclonal to CD137
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human CD137 aa 115-165 conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Sequence:

    KGCKDC CFGTFNDQKR GICRPWTNCS LDGKSVLVNG TKERDVVCGP SPADL


    Database link: Q07011

  • Positive control

    • Rat brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab203391 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Predicted molecular weight: 28 kDa.
IHC-P 1/100 - 1/600. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Use at 1/50 - 1/200 with fluorescent detection methods.

Target

  • Function

    Receptor for TNFSF14/4-1BBL. Possibly active during T cell activation.
  • Tissue specificity

    Expressed on the surface of activated T-cells.
  • Sequence similarities

    Contains 4 TNFR-Cys repeats.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 4 1BB antibody
    • 4 1BB ligand receptor antibody
    • 4-1BB ligand receptor antibody
    • 4-1BB Ligand Receptor T Cell antibody
    • 4-1BB, mouse, homolog of antibody
    • Antigen 4-1BB Homolog antibody
    • CD 137 antibody
    • CD137 antibody
    • CD137 antigen antibody
    • CDw137 antibody
    • HLDA VI antibody
    • Homolog of mouse 4 1BB antibody
    • ILA antibody
    • induced by lymphocyte activation (ILA) antibody
    • Induced by lymphocyte activation antibody
    • Interleukin activated receptor homolog of mouse Ly63 antibody
    • Ly63, mouse, homolog of antibody
    • MGC2172 antibody
    • OTTHUMP00000044294 antibody
    • Receptor protein 4 1BB antibody
    • T cell antigen 4 1BB homolog antibody
    • T cell antigen ILA antibody
    • T-cell antigen 4-1BB homolog antibody
    • T-cell antigen ILA antibody
    • TNF receptor superfamily member 9 antibody
    • TNFRSF9 antibody
    • TNR9_HUMAN antibody
    • Tumor necrosis factor receptor superfamily member 9 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded rat brain tissue, labeling CD137 using ab203391 at a 1/600 dilution, followed by conjugation to the secondary antibody and DAB staining.

References

This product has been referenced in:

  • Wang F  et al. CagA promotes proliferation and inhibits apoptosis of GES-1 cells by upregulating TRAF1/4-1BB. Mol Med Rep 16:1262-1268 (2017). Read more (PubMed: 28627614) »
  • Wang J  et al. PD-1 Blockade Prevents the Development and Progression of Carcinogen-Induced Oral Premalignant Lesions. Cancer Prev Res (Phila) 10:684-693 (2017). Read more (PubMed: 29018057) »
See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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