Anti-CD14 antibody [MEM-15], prediluted (Allophycocyanin/Cy7 ®) (ab194805)

Overview

  • Product name

    Anti-CD14 antibody [MEM-15], prediluted (Allophycocyanin/Cy7 ®)
    See all CD14 primary antibodies
  • Description

    Mouse monoclonal [MEM-15] to CD14, prediluted (Allophycocyanin/Cy7 ®)
  • Host species

    Mouse
  • Conjugation

    Allophycocyanin/Cy7 ®. Ex: 650nm, Em: 774nm
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human, Non human primates
  • Immunogen

    Other Immunogen Type corresponding to Human CD14. (A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.)

Properties

Applications

Our Abpromise guarantee covers the use of ab194805 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 4µl for 106 cells.

(or 100 μl of whole blood).

Target

  • Function

    Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
  • Tissue specificity

    Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
  • Sequence similarities

    Contains 11 LRR (leucine-rich) repeats.
  • Post-translational
    modifications

    N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD 14 antibody
    • CD_antigen=CD14 antibody
    • CD14 antibody
    • CD14 antigen antibody
    • CD14 molecule antibody
    • CD14_HUMAN antibody
    • LPS-R antibody
    • Mo2 antibody
    • Monocyte differentiation antigen CD14 antibody
    • Monocyte differentiation antigen CD14 urinary form antibody
    • Monocyte differentiation antigen CD14, membrane-bound form antibody
    • Myeloid cell specific leucine rich glycoprotein antibody
    • Myeloid cell-specific leucine-rich glycoprotein antibody
    see all

Images

  • Flow Cytometry analysis of Human peripheral blood cells labeling CD14 with Anti-CD14 antibody [MEM-15], prediluted (Allophycocyanin/Cy7 ®) (ab194805).

References

ab194805 has not yet been referenced specifically in any publications.

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