Anti-CD147 antibody [RL73] - Low endotoxin, Azide free (ab171273)
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Overview
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Product nameAnti-CD147 antibody [RL73] - Low endotoxin, Azide free
See all CD147 primary antibodies -
DescriptionRat monoclonal [RL73] to CD147 - Low endotoxin, Azide free
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Host speciesRat
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Tested applicationsSuitable for: Flow Cyt, IPmore details
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Species reactivityReacts with: Mouse
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Immunogen
The details of the immunogen for this antibody are not available.
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Positive control
- Mouse thymic cells.
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General notes
Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by the LAL assay.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
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Storage bufferConstituent: PBS
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Concentration information loading... -
PurityProtein G purified
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ClonalityMonoclonal
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Clone numberRL73
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IsotypeIgG2a
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Light chain typekappa
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Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab171273 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
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| Flow Cyt | Use 0.5µg for 105-8 cells. (Final test volume = 100 µL) ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
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| IP | Use at an assay dependent concentration. |
Target
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FunctionPlays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
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Tissue specificityPresent only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.
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Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
Post-translational
modificationsN-glycosylated. -
Cellular localizationCell membrane. Melanosome. Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
- Information by UniProt
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Database links
- Entrez Gene: 12215 Mouse
- SwissProt: P18572 Mouse
- Unigene: 431532 Mouse
- Unigene: 726 Mouse
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Alternative names
- 5A11 antigen antibody
- 5F7 antibody
- BASI_HUMAN antibody
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Datasheets and documents
References
ab171273 has not yet been referenced specifically in any publications.
