Anti-CD147 antibody [RL73] - Low endotoxin, Azide free (ab171273)

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Overview

  • Product name

    Anti-CD147 antibody [RL73] - Low endotoxin, Azide free
    See all CD147 primary antibodies

  • Description

    Rat monoclonal [RL73] to CD147 - Low endotoxin, Azide free

  • Host species

    Rat

  • Tested applications

    Suitable for: Flow Cyt, IPmore details

  • Species reactivity

    Reacts with: Mouse

  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control

    • Mouse thymic cells.

  • General notes

    Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by the LAL assay.

Properties

Applications

Our Abpromise guarantee covers the use of ab171273 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.5µg for 105-8 cells.

(Final test volume = 100 µL)

ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.

Target

  • Function

    Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.

  • Tissue specificity

    Present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.

  • Sequence similarities

    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.

  • Post-translational
    modifications

    N-glycosylated.

  • Cellular localization

    Cell membrane. Melanosome. Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

  • Database links

    • Alternative names

      • 5A11 antigen antibody
      • 5F7 antibody
      • BASI_HUMAN antibody
      • Basigin (Ok blood group) antibody
      • Basigin antibody
      • Blood brain barrier HT7 antigen antibody
      • Bsg antibody
      • CD 147 antibody
      • CD147 antibody
      • CD147 antigen antibody
      • Collagenase stimulatory factor antibody
      • EMMPRIN antibody
      • Extracellular matrix metalloproteinase inducer antibody
      • Leukocyte activation antigen M6 antibody
      • M 6 antibody
      • M6 antibody
      • M6 leukocyte activation antigen antibody
      • Neurothelin antibody
      • OK antibody
      • OK blood group antibody
      • OK blood group antigen antibody
      • TCSF antibody
      • Tumor cell derived collagenase stimulatory factor antibody
      • Tumor cell-derived collagenase stimulatory factor antibody
      see all

    References

    ab171273 has not yet been referenced specifically in any publications.

    Publishing research using ab171273? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

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    Question

    Could you tell me what buffer this product is in?
    If we wanted to dilute it, could you recommend a suitable buffer?

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    Answer

    The buffer is azide-free PBS, and this can be used for diluting the antibody.

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