Anti-CD151 antibody (ab201174)

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Overview

  • Product name

    Anti-CD151 antibody
    See all CD151 primary antibodies

  • Description

    Rabbit polyclonal to CD151

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-P, WBmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Synthetic peptide corresponding to Human CD151 (internal sequence).
    Database link: P48509

  • Positive control

    • HepG2 cell line lysate and human fetal heart tissue lysate. Human fetal colon tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab201174 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.
WB 1/500 - 1/1000. Predicted molecular weight: 28 kDa.

Target

  • Function

    Essential for the proper assembly of the glomerular and tubular basement membranes in kidney.

  • Tissue specificity

    Expressed in a variety of tissues including vascular endothelium and epidermis. Expressed on erythroid cells, with a higher level of expression in erythroid precursors than on mature erythrocytes.

  • Involvement in disease

    Defects in CD151 are the cause of nephropathy with pretibial epidermolysis bullosa and deafness (NPEBD) [MIM:609057]. NPEBD is characterized by the association of hereditary nephritis, epidermolysis bullosa, deafness, and beta-thalassemia minor.

  • Sequence similarities

    Belongs to the tetraspanin (TM4SF) family.

  • Cellular localization

    Membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • CD151 antibody
      • CD151 antigen antibody
      • CD151 molecule (Raph blood group) antibody
      • CD151 molecule antibody
      • CD151_HUMAN antibody
      • GP27 antibody
      • hemidesmosomal tetraspanin CD151 antibody
      • Membrane glycoprotein SFA-1 antibody
      • MER2 antibody
      • PETA-3 antibody
      • PETA3 antibody
      • Platelet endothelial tetraspan antigen 3 antibody
      • platelet surface glycoprotein gp27 antibody
      • Platelet-endothelial cell tetraspan antigen 3 antibody
      • Platelet-endothelial tetraspan antigen 3 antibody
      • RAPH antibody
      • Red blood cell antigen MER2 antibody
      • SFA 1 antibody
      • SFA1 antibody
      • Tetraspanin-24 antibody
      • Tspan-24 antibody
      • TSPAN24 antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD151 antibody (ab201174)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD151 antibody (ab201174)

      Immunohistochemical analysis of formalin fixed, paraffin embedded human fetal colon tissue labeling CD151 with ab201174 at a 1/100 dilution.

    • Western blot - Anti-CD151 antibody (ab201174)
      Western blot - Anti-CD151 antibody (ab201174)
      All lanes : Anti-CD151 antibody (ab201174) at 1/500 dilution

      Lane 1 : HepG2 cell line lysate
      Lane 2 : Human fetal heart tissuelysate

      Predicted band size: 28 kDa

    References

    ab201174 has not yet been referenced specifically in any publications.

    Publishing research using ab201174? Please let us know so that we can cite the reference in this datasheet.

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