Overview

Description

  • Nature

    Synthetic

Specifications

Our Abpromise guarantee covers the use of ab202990 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form

    Liquid
  • Additional notes

    This is the blocking peptide for ab109223

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

General Info

  • Alternative names

    • CD 16
    • CD 16a
    • CD16
    • CD16a
    • CD16a antigen
    • CD16B
    • CD16b antigen
    • Fc fragment of IgG
    • Fc fragment of IgG low affinity IIIa receptor
    • Fc fragment of IgG low affinity IIIa receptor (CD16)
    • Fc fragment of IgG receptor IIIa
    • Fc fragment of IgG, low affinity III, receptor (CD16)
    • Fc fragment of IgG, low affinity III, receptor for (CD16)
    • Fc fragment of IgG, low affinity IIIa, receptor (CD16)
    • Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
    • Fc fragment of IgG, low affinity IIIa, receptor for
    • Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
    • Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
    • Fc gamma R3
    • Fc gamma receptor III 2 (CD 16)
    • Fc gamma receptor III A
    • Fc gamma receptor IIIA
    • Fc gamma receptor IIIb (CD 16)
    • Fc gamma RIII
    • Fc gamma RIII alpha
    • Fc gamma RIII beta
    • Fc gamma RIIIa
    • Fc gamma RIIIb
    • Fc of IgG
    • Fc-gamma receptor III2 (CD 16)
    • Fc-gamma receptor III2 (CD16)
    • Fc-gamma receptor IIIb (CD16)
    • Fc-gamma RIII
    • Fc-gamma RIII-alpha
    • Fc-gamma RIIIa
    • FCG 3
    • FCG3
    • FCG3A_HUMAN
    • FCgammaRIIIA
    • FCGR 3
    • FCGR 3A
    • FCGR3
    • FCGR3A
    • FCGR3A protein
    • FCGRIII
    • FCGRIII-2
    • FcR 10
    • FcR-10
    • FcR10
    • FcRIII
    • FcRIIIa
    • IGFR 3
    • IGFR3
    • IgG Fc receptor III 1
    • IgG Fc receptor III 2
    • IgG Fc receptor III-2
    • IMD20
    • immunoglobulin G Fc receptor III
    • immunoglobulin G Fc receptor III-2
    • Low affinity IIIa receptor
    • Low affinity immunoglobulin gamma Fc region receptor III A
    • Low affinity immunoglobulin gamma Fc region receptor III-A
    • Low affinity immunoglobulin gamma Fc region receptor IIIB
    • neutrophil-specific antigen NA
    see all
  • Function

    Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
  • Tissue specificity

    Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
  • Sequence similarities

    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
  • Post-translational
    modifications

    Glycosylated. Contains high mannose- and complex-type oligosaccharides.
    The soluble form is produced by a proteolytic cleavage.
  • Cellular localization

    Cell membrane. Secreted. Exists also as a soluble receptor.
  • Information by UniProt

References

ab202990 has not yet been referenced specifically in any publications.

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