Overview

  • Product name

  • Description

    Rabbit polyclonal to CD168
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human CD168 aa 550-650. The exact sequence is proprietary. (Near C-terminus).
    Database link: O75330

  • Positive control

    • IHC-P: Human prostate carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab224768 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Primary incubation for 30 minutes at room temperature.

Target

  • Function

    Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the focal adhesion kinase occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.
  • Tissue specificity

    Expressed in breast cancer cell lines and in normal breast tissue.
  • Cellular localization

    Cell surface. Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD168 antibody
    • CD168 antigen antibody
    • HMMR antibody
    • HMMR_HUMAN antibody
    • Hyaluronan mediated motility receptor antibody
    • Hyaluronan-mediated motility receptor (RHAMM) antibody
    • IHABP antibody
    • Intracellular hyaluronic acid-binding protein antibody
    • MGC119494 antibody
    • MGC119495 antibody
    • OTTHUMP00000196920 antibody
    • Receptor for hyaluronan-mediated motility antibody
    • RHAMM antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human prostate carcinoma tissue stained for CD168 using ab224768 at 1/100 dilution in immunohistochemical analysis.

References

ab224768 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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