Anti-CD16+CD32 antibody [93] - Low endotoxin, Azide free (ab171202)

Overview

  • Product name

    Anti-CD16+CD32 antibody [93] - Low endotoxin, Azide free
    See all CD16+CD32 primary antibodies
  • Description

    Rat monoclonal [93] to CD16+CD32 - Low endotoxin, Azide free
  • Host species

    Rat
  • Tested applications

    Suitable for: Functional Studies, Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control

    • Mouse splenocyte suspensions.
  • General notes

    Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by the LAL assay.

     

Properties

Applications

Our Abpromise guarantee covers the use of ab171202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies Use at an assay dependent concentration.
Flow Cyt Use 0.5µg for 105-8 cells.

(in a final volume of 100 μL).

ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • Relevance

    Function: Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. Tissue specificity: Found on monocytes, neutrophils and eosinophil platelets. Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. PTM: Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
  • Cellular localization

    CD32: Type I membrane protein. CD16: Attached to the membrane by a GPI anchor. Exists also as a soluble receptor, produced by a proteolytic cleavage.
  • Database links

  • Alternative names

    • CD16a antibody
    • CD16b antibody
    • CD32 antibody
    • CD32A antibody
    • CD32B antibody
    • CDw32 antibody
    • Fc fragment of IgG low affinity IIa receptor antibody
    • Fc fragment of IgG low affinity IIb receptor antibody
    • Fc fragment of IgG low affinity IIIa receptor antibody
    • Fc fragment of IgG low affinity IIIb receptor antibody
    • Fc gamma receptor III A antibody
    • Fc gamma receptor IIIb antibody
    • Fc gamma RIIa antibody
    • Fc gamma RIIb antibody
    • Fc gamma RIII beta antibody
    • Fc-gamma RII-a antibody
    • Fc-gamma-RIIa antibody
    • FCG2A_HUMAN antibody
    • FcGR antibody
    • FCGR2A antibody
    • FCGR2B antibody
    • FCGR3 antibody
    • FCGR3A antibody
    • FCGR3B antibody
    • FcRII-a antibody
    • FcRIII antibody
    • IgG Fc receptor II-a antibody
    • Low affinity immunoglobulin gamma Fc region receptor II-a antibody
    see all

Images

  • Flow cytometric analysis of BALB/c splenocytes with 0.25 µg Rat IgG2a K Isotype Control (open histogram) or 0.25 µg ab171202 (filled histogram) followed by Anti-Rat IgG FITC. Total viable cells were used for analysis.

     

References

ab171202 has not yet been referenced specifically in any publications.

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