Overview

  • Product name

    Anti-CD172 gamma antibody [OX117]
    See all CD172 gamma primary antibodies
  • Description

    Rabbit monoclonal [OX117] to CD172 gamma
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Flow Cytmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein. Recombinant humanCD172 gamma fusion protein (Purified).

  • Positive control

    • Flow Cyt: Human lymphocytes.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.02% Proclin
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Monoclonal
  • Clone number

    OX117
  • Isotype

    IgG
  • Light chain type

    lambda
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab245690 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use a concentration of 1 µg/ml.

Target

  • Function

    Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
  • Tissue specificity

    Detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. Mainly present in the paracortical T-cell area of lymph nodes, with only sparse positive cells in the mantle and in the germinal center of B-cell follicles. In the thymus, primarily expressed in the medulla on mature T lymphocytes that have undergone thymic selection.
  • Sequence similarities

    Contains 2 Ig-like C1-type (immunoglobulin-like) domains.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD172 antigen like family member B antibody
    • bA77C3.1 antibody
    • CD172 antigen-like family member B antibody
    • CD172g antibody
    • CD172g antigen antibody
    • FLJ42230 antibody
    • RP11-77C3.2 antibody
    • Signal regulatory protein beta 2 antibody
    • Signal regulatory protein gamma antibody
    • Signal-regulatory protein beta-2 antibody
    • Signal-regulatory protein gamma antibody
    • SIRP B2 antibody
    • SIRP beta 2 antibody
    • SIRP gamma antibody
    • SIRP-b2 antibody
    • SIRP-beta-2 antibody
    • SIRP-gamma antibody
    • SIRPB2 antibody
    • SIRPG antibody
    • SIRPG_HUMAN antibody
    • SIRPgamma antibody
    see all

Images

  • Human lymphocytes were stained with an isotype control (Panel A) or ab245690 (Panel B) at a concentration of 1 µg/ml for 30 mins at RT. After washing, bound antibody was detected using an AF488 conjugated donkey anti-rabbit antibody (ab150073).

References

ab245690 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab245690.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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