Overview

  • Product name

    Anti-CD1a antibody [C1A/711]
    See all CD1a primary antibodies
  • Description

    Mouse monoclonal [C1A/711] to CD1a
  • Host species

    Mouse
  • Tested applications

    Suitable for: WB, IHC-P, IHC-Fr, Flow Cyt, IP, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human CD1a.
    Database link: P06126

  • Positive control

    • Human skin tissue. MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituents: 99% PBS, 0.05% BSA
  • Concentration information loading...
  • Purity

    Protein A/G purified
  • Purification notes

    ab201337 is purified from Bioreactor Concentrate.
  • Clonality

    Monoclonal
  • Clone number

    C1A/711
  • Isotype

    IgG1
  • Light chain type

    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab201337 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 37 kDa.
IHC-P Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

For 30 min at RT.

IHC-Fr Use a concentration of 0.5 - 1 µg/ml.

For 30 min at RT.

Flow Cyt Use 0.5-1µg for 106 cells.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

IP Use at 2-4 µg/mg of lysate.
ICC/IF Use a concentration of 1 - 2 µg/ml.

Target

  • Function

    Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
  • Tissue specificity

    Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues.
  • Sequence similarities

    Contains 1 Ig-like (immunoglobulin-like) domain.
  • Cellular localization

    Cell membrane. Endosome membrane. Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD 1a antibody
    • CD1 antibody
    • CD1a antibody
    • CD1A Antigen antibody
    • CD1A antigen, a polypeptide antibody
    • CD1a molecule antibody
    • CD1A_HUMAN antibody
    • cluster of differentiation 1 A antibody
    • cortical thymocyte antigen CD1A antibody
    • differentiation antigen CD1 alpha 3 antibody
    • epidermal dendritic cell marker CD1a antibody
    • FCB 6 antibody
    • FCB6 antibody
    • HTA 1 antibody
    • HTA1 antibody
    • hTa1 thymocyte antigen antibody
    • OTTHUMP00000018907 antibody
    • R 4 antibody
    • R4 antibody
    • T 6 antibody
    • T-cell surface antigen T6/Leu-6 antibody
    • T-cell surface glycoprotein CD1a antibody
    • T6 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin tissue labeling CD1a with ab201337 at 1 µg/ml.

References

This product has been referenced in:

  • Gellén E  et al. 5-Aminolevulinic acid photodynamic therapy with and without Er:YAG laser for actinic keratosis: Changes in immune infiltration. Photodiagnosis Photodyn Ther 26:270-276 (2019). Read more (PubMed: 30986538) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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